_____________________________________________________________________________________________________ *Corresponding author: E-mail: dipankar.bhattacharyay@cutm.ac.in; Journal of Pharmaceutical Research International 32(6): 128-131, 2020; Article no.JPRI.56450 ISSN: 2456-9119 (Past name: British Journal of Pharmaceutical Research, Past ISSN: 2231-2919, NLM ID: 101631759) Capsicum Derived Phytochemicals against Shikimate Dehydrogenase of Haemophilus influenza causing Bronchitis Debesh Kumar Hota 1 , Debadatta Nayak 1 , Sitaram Swain 1 and Dipankar Bhattacharyay 1,2* 1 Centurion University of Technology and Management, Odisha, India. 2 Go to Market Laboratory, Gram Tarang, Odisha, India. Authors’ contributions This work was carried out in collaboration among all authors. All authors read and approved the final manuscript. Article Information DOI: 10.9734/JPRI/2020/v32i630507 Editor(s): (1) Dr. Syed A. A. Rizvi, Nova Southeastern University, USA. Reviewers: (1) Sandeep Onkar Waghulde, University of Mumbai, India. (2) Bhaskar Sharma, Suresh Gyan Vihar University, India. Complete Peer review History: http://www.sdiarticle4.com/review-history/56450 Received 09 April 2020 Accepted 13 May 2020 Published 15 May 2020 ABSTRACT Phytochemicals from Capsicum plant extract are traditionally used to cure Bronchitis. It is caused by Haemophilus influenzae. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that Apigenin can effectively deactivate the Shikimate dehydrogenase enzyme thereby interrupting the life cycle of the organism. Keywords: Phytochemical; capsicum; Haemophilus influenza. 1. INTRODUCTION In olden days, life was natural, slow, difficult at times but healthy. Today, in modern times, life is fast paced, comfortable, readymade, stressful and unhealthy. Nature is a major source of medicines [1]. The medicinal value of the plants is due to the phytochemicals present in it. Phytochemicals can be derived from different parts of plants.Different medicinal plants and their phytoextracts have shown anti-microbial action [2]. These medicinal plants play a key role Original Research Article