_____________________________________________________________________________________________________ *Corresponding author: E-mail: niaz_h@hotmail.com; Journal of Pharmaceutical Research International 33(47A): 724-730, 2021; Article no.JPRI.76118 ISSN: 2456-9119 (Past name: British Journal of Pharmaceutical Research, Past ISSN: 2231-2919, NLM ID: 101631759) Outcomes of Ilizarov Ring Fixator in Infected Nonunion of Tibia Muhammad Hamayun Hameed 1 , Abdul Hamid Kakar 1 , Hassan Amir Us Saqlain 2 , Syed Sajid Hussain 2 , Masood Ahmed Qureshi 3 , Niaz Hussain Keerio 4* and Syed Shahid Noor 5 1 Bolan Medical Complex Hospital, Quetta, Pakistan. 2 Al Qassimi Hospital Sharjah, United Arab Emirates. 3 King Abdul Aziz Hospital Makkah, Saudi Arabia. 4 Muhammad Medical College and Hospital Mirpurkhas, Pakistan. 5 Department Orthopedic, Liaquat National Hospital and Medical College, Karachi, Pakistan. Authors’ contributions This work was carried out in collaboration among all authors. All authors read and approved the final manuscript. Article Information DOI: 10.9734/JPRI/2021/v33i47A33067 Editor(s): (1) Dr. Sawadogo Wamtinga Richard, Ministry of Higher Education, Scientific Research and Innovation, Burkina Faso. Reviewers: (1) Andrija Karačić, Clinical Hospital Sveti Duh, Croatia. (2) Swapna Manepalli, NTR University, India. Complete Peer review History: https://www.sdiarticle4.com/review-history/76118 Received 20 August 2021 Accepted 27 October 2021 Published 29 October 2021 ABSTRACT Objective: This study was designed to evaluate the effectiveness of Ilizarov. We aimed to explore the infection rate, bony union, and functional outcomes of Ilizarov fixators. Methodology: This retrospective study was conducted in Orthopedic department of Bolan Medical Complex Hospital Quetta Pakistan from June 2020 to June 2021. In this timeframe total of fifty-five patients of infected nonunion tibia were enrolled for Ilizarov technique treatment. For surgical intervention, patients were placed in a supine position on a radiolucent table. Ilizarov fixator was prepared on the behalf of patient's limb length, infection site, and ankle and knee functional status. We applied assembled Ilizarov fixator at the tibial shaft while keeping in mind that the rings were positioned in on the proximal and distal fragments. The ring was placed parallel to the joints whereas pins were inserted perpendicular to the tibial mechanical axis. Results: A total of 55 patients were recruited for this study. The mean age of the selected Original Research Article