Bhuwan Sharma et al JMSCR Volume 04 Issue 08 August Page 11814 JMSCR Vol||04||Issue||08||Page 11814-11817||August 2016 Study of Asymptomatic Peripheral Arterial Disease in Ischemic Stroke Patients and Associated Comorbid Conditions Authors Bhuwan Sharma 1 , Surekha Dabla 2 , Anubha Garg 3 Kapinder Yadav 1 1 Post Gradute Resident Medicine, PGIMS Rohtak. 2 Senior Professor Medicine, PGIMS Rohtak 3 Assistant Professor Medicine, PGIMS Rohtak Corresponding Author Dr Bhuwan Sharma Doctor’s Hostel, PGIMS Rohtak, Haryana India Email: drbhuwan_86@yahoo.com, 9812317569 ABSTRACT Patients with stroke and patients with transient ischemic attack (TIA) are at high risk for vascular events and may not exhibit the signs and symptoms of peripheral arterial disease (PAD). We investigated prevalence of asymptomatic PAD detected by ankle brachial index <0.9 in patients with stroke and difference between risk factor profile between patient having asymptomatic PAD and those without asymptomatic PAD. In this cross sectional hospital-based study, asymptomatic PAD was detected by ankle brachial index measurement in consecutive 100 patients with stroke. They were assessed for stroke risk factors, ankle brachial index measurement, and laboratory parameters known to be associated with stroke risk. These data was compared between patient having asymptomatic PAD and those without asymptomatic PAD. Our study demonstrates that in patients with ischemic stroke, asymptomatic peripheral arterial disease is highly prevalent. These patients had significantly higher risk factors and risk of future athero-thrombotic events could be higher, so ABI measurement can be good non-invasive tool to identify patients with greater risk of future events and thereby help in optimizing secondary preventive measures. Key words: Stroke, Ankle brachial index, Peripheral arterial disease INTRODUCTION Peripheral arterial disease (PAD) is frequently present in patients with stroke; with a prevalence ranging between 24.1 and 51.0 % 1 . The most widely used method to detect peripheral arterial disease is the measurement of the ankle brachial index (ABI). An ABI of ≤ 0.90 is diagnostic of PAD 2 . Several studies in the general population showed that an ABI of ≤ 0.90 is independently associated with increased incidence of cardiovascular events, and stroke 3 . Moreover, the lower the ABI value, the higher the risk of overall cardiac and cerebrovascular death in patients with peripheral vascular disease 4 . In this study, we determined the prevalence of asymptomatic peripheral arterial disease in ischemic stroke patients at a tertiary care centre, by measuring ABI of 100 patients with ischemic stroke and investigated the association of ABI with age, gender, risk factors, associated co- morbidities and type of stroke. www.jmscr.igmpublication.org Impact Factor 5.244 Index Copernicus Value: 83.27 ISSN (e)-2347-176x ISSN (p) 2455-0450 DOI: http://dx.doi.org/10.18535/jmscr/v4i8.20