Probing protein phosphatase substrate binding: Affinity pull-down of ILKAP
phosphatase 2C with phosphopeptides
Kim B. Højlys-Larsen
*a
, Kasper K. Sørensen
a b
, Knud J. Jensen
*b
and Steen Gammeltoft
a
Received (in XXX, XXX) Xth XXXXXXXXX 20XX, Accepted Xth XXXXXXXXX 20XX
DOI: 10.1039/b000000x
Supplementary Information
Content:
Fig S1: Comparison of pull-down performed at 4ºC and 30 ºC.
Table S1: Mass spectrometric characterization of phosphopeptides 1-28.
Table S2: Summary of ILKAP pull-down specificity for dephosphorylation targets
Table S3-S7: Western Blot quantification data
[a] Dr. K. B. Højlys-Larsen, Dr. K. K. Sørensen, Prof. S. Gammeltoft
Department of Clinical Biochemistry
Glostrup Hospital
Ndr. Ringvej, 2600 Glostrup, (Denmark)
Fax: (+45) 38 63 39 58
E-mail: kimlar01@regionh.dk
[b] Dr. K. K. Sørensen, Prof. K. J. Jensen
Faculty of Science, University of Copenhagen
40 Thorvaldsensvej, 1871 Frederiksberg (Denmark)
E-mail:kjj@life.ku.dk
Electronic Supplementary Material (ESI) for Molecular BioSystems
This journal is © The Royal Society of Chemistry 2012