Research report The tale of two genes: from next-generation sequencing to phenotype Mersedeh Rohanizadegan 1 , Aishwarya Siddharath 1 , Kyle Retterer 2 , Christina Hung 1 , Olaf Bodamer 1,3 1 Division of Genetics and Genomics, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts 02115; 2 GeneDx Gaithersburg, MD 20877; 3 Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142; Short running title: Bohring-Opitz Syndrome and monogenic obesity Corresponding author: Olaf Bodamer MD PhD Division of Genetics and Genomics Boston Children’s Hospital Hunnewell 539 300 Longwood Ave Boston, MA 02115 Tel: 857 218 5544 E-mail: olaf.bodamer@childrens.harvard.edu Cold Spring Harbor Laboratory Press on July 24, 2020 - Published by molecularcasestudies.cshlp.org Downloaded from