Cronicon OPEN ACCESS EC NEUROLOGY EC NEUROLOGY Research Article Curative Embolization of Small Brain Arteriovenous Malformation by Non-Adhesive Liquid (Ethyl Vinyl Alcohol Copolymer): A Retrospecive Study from Tertiary Care Centre Sharad B Ghatge 1,2 *, Nirmal S Surya 3 , Nootan K Sharma 4 and Dhaval B Modi 2 1 Division of Interventional Radiology, Department of Radiology and Imaging, Grant Government Medical College and Sir JJ Group of Hospitals, Mumbai, India 2 Department of Interventional Neuroradiology, Bombay Hospital, Mumbai, India 3 Department of Neurology, Bombay Hospital, Mumbai, India 4 Honorary Consultant Neurosurgeon, LH Hiranandani Hospital and Ex. Department of Neurosurgery, Bombay Hospital, Mumbai, India Citation: Sharad B Ghatge., et al. “Curative Embolization of Small Brain Arteriovenous Malformation by Non-Adhesive Liquid (Ethyl Vinyl Alcohol Copolymer): A Retrospecive Study from Tertiary Care Centre”. EC Neurology 12.8 (2020): 58-76. *Corresponding Author: Sharad B Ghatge, Division of Interventional Radiology, Department of Radiology and Imaging, Grant Government Medical College and Sir JJ Group of Hospitals, Mumbai, India. Received: July 02, 2020; Published: July 15, 2020 Abstract Background and Objective: A Randomised trial of Unruptured Brain Arteriovenous malformations (ARUBA) trial has favoured treatment of unruptured AVM by best medical management alone. However critics have generally accepted treatment of Low grade AVM by neurosurgery and deep, eloquent AVM by radiosurgery. Objective of this study is to retrospectively examine effectiveness of embolization by non adhesive liquid embolic agent (ethyl vinyl alcohol copolymer) for complete cure of small Brain AVM. Methods: We retrospectively analyzed patients with small brain AVM treated by embolization during January 2008 to January 2020. The primary goal was to cure it completely. There were 16 patients with 9 males and 7 females. Their age was ranging from 18 to 38 years with mean of 30 years. There were 5 patients with ruptured and 11 with unruptured AVM. Results: Twenty embolization sessions were done in 16 patients. Twelve patients had undergone single session each and 4 patients with two sessions each. Fifteen out of sixteen patients were cured completely with embolization alone (93.75% Obliteration rate). The one patient (6.25%) required SRS to achieve complete cure for the residual AVM after two sessions of embolization. Non perma- nent complication rate was 18.75%. There were no deaths. Conclusion: Embolization of small brain AVM with intension to cure by non Adhesive liquid embolic agent can deliver obliteration rate of 93.75%. Complication rate associated with embolization in our small retrospective study is 18.75% with no permanent dis- ability or deaths. Keywords: Curarive Embolization; Brain AVM; Non-Adhesive Embolic Liquid (EVOH) Abbreviations AVM: Arteriovenous Malformation; EVOH: Ethyl Vinyl Alcohol Copolymer; DMSO: Dimethyl Sulfoxide; NBCA: N-Butyl Cyanoacrylate Glue; SRS: Stereotactic Radiosurgery Introduction Brain arterio-venous malformation(AVM) is tuft of abnormal vessels supplied by artery and drained by vein with arterio-venous shun- ting. They should be considered genetically acquired as genetic susceptibility kick starts nascent focus and environmental triggers acting