University of P ´ ecs Ph.D. Thesis Platelet and platelet-derived microparticle studies in severe sepsis Author: G´aborL´aszl´o Woth M.D. Supervisors: Univ. Prof. G´abor L. Kov ´ acs M.D. Ph.D., D.Sc., member of HAS Diana M¨ uhl M.D. Ph.D. Department of Anaesthesiology and Intensive Therapy, Department of Laboratory Medicine March 2013