Open Access Review Article Journal of Dental Health and Oral Research Balamanikandan P | Volume 2; Issue 3 (2021) | JDHOR-2(3)-037 | Review Article Citation: Salian V, et al. Special Stains in Histopathology: An Oral Pathology Perspective. J Dental Health Oral Res. 2021;2(3):1-19. DOI: http://dx.doi.org/10.46889/JDHOR.2021.2306 Special Stains in Histopathology: An Oral Pathology Perspective Balamanikandan P 1 , Varsha Salian 2* , Pushparaja Shetty 3 1 Post Graduate, NITTE (Deemed to be University), AB Shetty Memorial institute of Dental Sciences (ABSMIDS), Department of Oral and Maxillofacial Pathology, Mangalore, Karnataka, India 2 Reader, NITTE (Deemed to be University), AB Shetty Memorial institute of Dental Sciences (ABSMIDS), Department of Oral and Maxillofacial Pathology, Mangalore, Karnataka, India 3 Professor and Head, NITTE (Deemed to be University), AB Shetty Memorial institute of Dental Sciences (ABSMIDS), Department of Oral and Maxillofacial Pathology, Mangalore, Karnataka, India * Corresponding Author: Varsha Salian, Reader, NITTE (Deemed to be University), AB Shetty Memorial institute of Dental Sciences (ABSMIDS), Department of Oral and Maxillofacial Pathology, Mangalore, Karnataka, India; Email: varu_2002@yahoo.com Received Date: 16-11-2021; Accepted Date: 12-12-2021; Published Date: 20-12-2021 Copyright © 2021 by Balamanikandan P, et al. All rights reserved. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited. Abstract Stains play a vital role in any histopathological laboratory. The term "stain" denotes any dye, reagent, or material that is used for colouring tissues and microorganisms to aid in the microscopic study. Hematoxylin and eosin are the basic, routine and universal stains used in all laboratories. But, specific components, structures, or substances of the tissue can accept only a particular specific type of stain based on their chemical and biological structure or nature. In such cases the use of a special stain is inevitable. Various special stains are being used in histopathological laboratories. We conducted a computerized database search in Pubmed and Google scholar to identify and collect data regarding special stains. Here in this article, we present a brief overview of special stains used in oral pathology. Keywords Cytology; Hematology; Histochemistry; Histological Technique; Tissue Stains