Aspiring A Cutting Edge Research Journal of Biomedical and Biological Sciences Ishtiaq I, et al., J. Biomed. Biol. Sci. 2021, 1:1 Review Article Open Access J. Biomed. Biol. Sci.- Open Access Journal Volume 1(1): 1-8 (2021) - Page No.1 ©Science and Innova�on(SNI) publica�ons under Common Crea�ve License A Review on Novel Coronavirus Covid-19: Its Detection and Vaccination Isha Ishtiaq 1* , Sana Shahzadi 1 , Ayesha Afzal 1 , Sara Khan 1 , Zoya Ahmed 1 , Saman Gulrez 1 , Mohsin Nawaz 1 , Momina Sajjad 2 and Nimra Razzaq 1 1 Department of Biotechnology, University of Sialkot, Sialkot, Pakistan. 2 Department of Microbiology, University of Central Punjab, Lahore, Pakistan. * Corresponding Author: Ishtiaq I, Department of Biotechnology, University of Sialkot, Sialkot, Pakistan. E-mail: ishaishtiaq@gmail.com Citation: Ishtiaq I, Shahzadi S, Afzal A, Khan S, Ahmed Z, et al. A Review on Novel Coronavirus Covid-19: Its Detection and Vaccination. Journal of Biomedical and Biological Sciences. 2021;1(1):1-8. Copyright: © 2021 Ishtiaq I, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Received Date: 6 th July, 2021 Accepted Date: 22 nd November, 2021 Published Date: 2 nd December, 2021 Coronaviruses are enveloped, non-segmented, positive single stranded RNA viruses. In the history, SARS CoV have caused about 774 deaths globally with 8096 reported cases in 2003. MERS CoV (Middle eastern respiratory syndrome coronavirus) pandemic resulted in 33.5% fatality rate worldwide. SARS-CoV-2 genome consists of 5' untranslated region (5'UTR) and a replicase complex (orfab1) that encodes non-structural proteins (nps). About 5.06 million people have died of covid-19. Covid-19 transmission occurs more in closed environments than in open-air environments. High temperature and high humidity can greatly reduce the transmission of virus. Most common symptoms are fever, cough and fatigue but there are also unique symptoms like sneezing and sore throat. Covid-19 has created a devastating efect on the whole world. Its early detection is necessary to control the rapid spread of the disease. Computed tomography (CT) cannot detect the disease at early stages, so AI-based approaches are preferred. Many vaccines have been developed to protect against covid-19. There were 1,273,560 confrmed cases of COVID-19 in Pakistan between 3 January 2020 and 2 November 2021. A total of 103,238,614 vaccine doses has been administered as of 30 October 2021. Covid-19 Vaccine hesitancy is however, a global concern that afects both rich and poor countries. Identifying COVID-19 vaccine reluctance might aid in the design of public education initiatives aimed at improving vaccination acceptance behaviours. Fake news regarding the Coronavirus vaccines misleads the public's perception, making it difcult to limit the virus and gain public trust. Keywords: Covid-19, Vaccine, Hesitancy, Detection techniques, SARS-CoV Abstract