International Journal of Engineering and Advanced Technology (IJEAT)
ISSN: 2249 – 8958, Volume-8 Issue-6, August 2019
5206
Published By:
Blue Eyes Intelligence Engineering
& Sciences Publication
Retrieval Number F8215088619/2019©BEIESP
DOI: 10.35940/ijeat.F8215.088619
Abstract: Alzheimer's disease (AD) is a degenerative brain
disease, a common health problem in elderly pesople which causes
decline in memory and affected on nerve cells. AD has different
stages like mild congestive impairment (MIC) (early stage),
moderate (middle stage), severe (late stage) it is essential to detect
AD early in MIC, so that pre-emptive measures can be taken.
Significant research was carried out over the past century to
diagnose and detect this disease early. The objective of the article
is provide a review evaluation and critical analysis of the recent
research work done to early diagnosis of AD using Machine
Learning Strategies.
Keywords: Alzheimer disease, Classification, Machine Learning
I. INTRODUCTION
Alzheimer's disease (AD) is a brain degenerative disease.
It is a effect on human thoughts and work. It is also caused by
the other diseases and conditions. Like a decline in memory,
effected on nerve cells. Neuronal damage in Alzheimer's
disease consequently impacts parts of the brain that allow an
person to perform general body activities such as walking,
swallowing eating etc [22]. Dementia is a term describing a
variety of disorders, and there are many various types of
dementia, such as Alzheimer's disease, dementia with Lowy
bodies and vascular dementia, and others. Dementia of the
type (AD) of Alzheimer's disease is by far the most common
cause of dementia. It is widely acknowledged that early
detection of dementia can lead to more effective intervention
and morbidity constraint Their research concludes that
people who encounter MCI criteria can be differentiated from
healthy control subjects and those with very mild Alzheimer's
disease. It appears that this group of subjects is a clinical
entity that can described for therapy measures.
To date, most mental disorder types have been diagnosed
based on clinical observation. In specific, those include
recognition of disorders that tend to cluster together, the
timing of disease appearance and their tendency to cure,
persist or be chronic. Currently there are no effective and
efficient diagnostic tools not available to detect Alzheimer’s.
Boise et al. acknowledge prior research of low levels of
clinical evaluation and diagnosis and conclude a possible
explanation for this in the originality of the symptoms of
dementia associated with the constraints encountered by
Revised Manuscript Received on August 05, 2019
G Stalin Babu, Dept of CSE, Aditya Institute of Technology and
Management, Tekkali, A.P., India.
S N Tirumala Rao, Dept of CSE, Narasaraopeta Engg College.
Narasaraopeta , A.P., India.
R Rajeswara Rao, Dept of CSE,JNTUK University College of
Engineering, Vizianagaram, A.P., India
physicians in their clinical practice. Through modern
neuropsychological and cognitive testing, Alzheimer's
disease is clinically diagnosed and other evidence of
intellectual deficiency is verified [25]. According to Dubois
et al., in addition to the clinical measures, the
recommendations for the diagnosis of Alzheimer's disease
accentuate the role that distinct biomarkers can perform. Like
Computerized Tomography (CT), Magnetic Resonance
Imaging (MRI), Positron Emission Tomography (PET),
Single Photon Emission Computed tomography (SPECT)
etc., Genetic risk profiles are analysed although they are
costly and complex to measure to large amounts of
evaluations. There is no specific test that can prove whether a
individual has Alzheimer's disease or not [23]. While
physicians always can evaluate whether an person has
dementia, the actual cause can be difficult to determine.
Alzheimer's disease immunology and risk parameters make
up 50% to 60% of all dementia situations in the modern world
today. Some of the other causes of dementia are vascular,
lewd body and frontal lobe.The incidence of dementia rises
with age, from 1% in 60-64 to 24-33% in those 85 years of
age or elder. Around 24.3 million persons suffered from
dementia in 2001, which is predicted to double every two
decades as life expectancy also rises to 81.1 million in 2040.
Western Europe, the USA and China are the nations and
regions of the globe that are most
impacted.By 2040, 55.7% of the total population impacted
will be ho me to these nations and regions
II. ALZHEIMER’S DIESES
A. Alzheimer's early signs and symptoms [20]
Memory loss that disrupts everyday life
Obstacles in planning or solving problems
Difficulty in understanding visual pictures
and partial relationships
New issues with phrases in talking or writing
Reduced or poorly judged
losing the ability to retrace steps and Misplacing
Things
Withdrawal from job or social activities
Difficulty in finishing familiar duties at home
And at job or at leisure
Changes in state of mind and character
Exploring of Classification Methods for Early
Detection of Alzheimer’s Disease
G Stalin Babu , S N Tirumala Rao , R Rajeswara Rao