~ 1 ~ International Journal of Pharmacognosy and Life Science 2020; 1(2): 01-05 E-ISSN: 2707-2835 P-ISSN: 2707-2827 IJPLS 2020; 1(2): 01-05 Received: 13-05-2020 Accepted: 16-06-2020 Dr. Charu Bansal Professor, P.G. Department of Swasthavritta, Pt. KLS Govt. Ayurveda College & Institution, Bhopal Madhya Pradesh, India Dr. Rachna Jain Professor & HOD Department of Swasthavritta, R.D. Memorial P.G. Ayurveda College & Hospital, Bhopal, Madhya Pradesh, India Dr. Umesh Shukla Head P.G. Department of Panchakarma, Principal, Pt. KLS Govt. Ayurveda College & Institution, Bhopal, Madhya Pradesh, India Dr. Smita Paul Professor & HOD Department of Roga Nidan Evam Vikriti Vigyan, R.D. Memorial P.G. Ayurveda College & Hospital, Bhopal, Madhya Pradesh, India Corresponding Author: Dr. Charu Bansal Professor, P.G. Department of Swasthavritta, Pt. KLS Govt. Ayurveda College & Institution, Bhopal Madhya Pradesh, India Preventive scope of Nishamalaki Churna (combination of turmeric and Indian gooseberry powder) in type 2 DM: Review Dr. Charu Bansal, Dr. Rachna Jain, Dr. Umesh Shukla and Dr. Smita Paul DOI: https://doi.org/10.33545/27072827.2020.v1.i2a.10 Abstract Diabetes mellitus is a fastest growing serious global health problem. In 2000, India with 31.7 million diabetic population topped the world followed by China (20.8 million) respectively. Poor glycaemic control has been observed in the Indian diabetic population which in long term lead to various micro and macro vascular complications. Diabetes is one of four priority non-communicable diseases (NCDs) targeted by all health agencies for the Prevention and Control of NCDs. Turmeric (Curcuma longa) and Indian Gooseberry (Emblica officinalis) powder in combination called as Nisha Amalaki Churna showed significant hypoglycemic, antioxidant and hyperlipidemia effect in many experimental and human research. Ayurveda strongly recommended its significant effect in the management of diabetes (Prameha). The present write up is an effort to discuss the opportunities of an effective herbal combination Nishamalaki Churna as preventive and health promotive dimensions in Type 2 Diabetes Mellitus. Keywords: nishamalaki churna, haridra, curcuma longa, emblica officinalis, amalaki, type 2 DM prevention 1. Introduction Diabetes mellitus is a fastest growing serious global health problem that affects all ages with high prevalence rate which have been steadily increasing over the past few decades. Diabetes is fast gaining the status of a potential epidemic in India. In 2014 WHO estimated, 422 million people in the world had diabetes with prevalence of 8.5% among the adult population. Word health Organization also reported that Diabetes caused 1.5 million deaths in 2012 and by increasing the risks of cardiovascular and other diseases blood glucose Higher-than-optimal caused an additional 2.2 million deaths. In which 3.7 million deaths (43%) occur before the age of 70 years [1] . Type 2 diabetes is also identified as or adult- onset diabetes develop due to ineffective use of insulin by body. Symptoms of Type 2 diabetes often less marked or absent in beginning. So, most of the time the disease remains undiagnosed for several years, until complications have already arisen. Impaired glucose tolerance (IGT) and impaired fasting glycaemia (IFG) are intermediate conditions in the transition between normal blood glucose levels and type 2 diabetes, though the transition is unexpected thus those are affected with IGT or IFG are simultaneously at increased risk of heart attacks and strokes. 1.1 long term complications developed due to diabetes Diabetes is an important cause of premature death and disability. In long term it can lead to complications like it can damage the heart, blood vessels, eyes, kidneys and nerves, and cause heart attack, stroke, kidney failure, leg amputation, vision loss and nerve damage. Diabetic retinopathy is an important cause of blindness and occurs as a result of long- term accumulated damage to the small blood vessels in the retina. Number of research indicating that beyond these traditional complications, diabetes has been also associated with increased rates of specific cancers, and increased rates of physical and cognitive disability [2] .