ORIGINAL ARTICLE Real-world evidence of biologic treatments in moderate–severe psoriasis in Italy: Results of the CANOVA (EffeCtiveness of biologic treAtmeNts for plaque psOriasis in Italy: An obserVAtional longitudinal study of real-life clinical practice) study Delia Colombo 1 | Luca Bianchi 2 | Gabriella Fabbrocini 3 | Salvatore Corrao 4 | Annamaria Offidani 5 | Luca Stingeni 6 | Antonio Costanzo 7 | Giovanni Pellacani 8 | Ketty Peris 9 | Federico Bardazzi 10 | Giuseppe Argenziano 11 | Silvana Ruffolo 12 | Paolo Dapavo 13 | Carlo Carrera 14 | Maria Concetta Fargnoli 15 | Aurora Parodi 16 | Marco Romanelli 17 | Piergiorgio Malagoli 18 | Marina Talamonti 2 | Matteo Megna 3 | Massimo Raspanti 4 | Matteo Paolinelli 5 | Katharina Hansel 6 | Alessandra Narcisi 7 | Andrea Conti 8 | Clara De Simone 9 | Marco Adriano Chessa 10 | Alina De Rosa 11 | Eugenio Provenzano 12 | Michela Ortoncelli 13 | Chiara Moltrasio 14 | Rosaria Fidanza 15 | Martina Burlando 16 | Annalisa Tonini 17 | Francesca Maria Gaiani 18 | Lucia Simoni 19 | Alessandra Ori 20 | Martina Fiocchi 1 | Emanuela Zagni 1 1 Market Access, Novartis Farma S.p.A, Origgio, Italy 2 Dermatology, Policlinico Tor Vergata, Rome, Italy 3 Dermatology, A.O.U. Federico II, Naples, Italy 4 Internal Medicine, ARNAS Civico, Palermo, Italy 5 Dermatology, A.O.U. Riuniti Umberto I Lancisi Salesi, Ancona, Italy 6 Dermatology Section, Department of Medicine and Surgery, University of Perugia, Perugia, Italy 7 Dermatology, IRCCS Istituto Clinico Humanitas, Rozzano, Italy 8 Dermatology, A.O.U. Policlinico, Modena, Italy 9 Dermatology, Fondazione Policlinico Universitario A. Gemelli-IRCCS e Università Cattolica, Rome, Italy 10 Dermatology, A.O.U. Policlinico S.Orsola-Malpighi, Bologna, Italy 11 Dermatology Unit, University of Campania, Naples, Italy 12 Dermatology, A.O. Cosenza Ospedale SS Annunziata, Cosenza, Italy 13 Dermatology, A.O.U. Città della Salute e della Scienza PO Molinette, Turin, Italy 14 Dermatology, Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico, Milan, Italy 15 Dermatology, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy 16 Dermatology, Clinica Dermatologica DiSSal Università di Genova/Ospedale-Policlinico San Martino IRCCS, Genoa, Italy 17 Dermatology, A.O.U. Pisana Ospedale Santa Chiara, Pisa, Italy 18 Dermatology, Policlinico San Donato, San Donato Milanese, Italy 19 Clinical Data Management and Statistics, MediNeos Observational Research, Modena, Italy 20 Clinical Operations, MediNeos Observational Research, Modena, Italy Received: 26 November 2020 Revised: 1 October 2021 Accepted: 15 October 2021 DOI: 10.1111/dth.15166 Dermatologic Therapy. 2021;e15166. wileyonlinelibrary.com/journal/dth © 2021 Wiley Periodicals LLC. 1 of 12 https://doi.org/10.1111/dth.15166