Case Series Mycosis Fungoides: Analysis of Ophthalmologic Findings in a Series of Cases Carina G. Colossi, 1 Juliano Mondadori, 2 Pedro K. M. Barreto, 2 Felipe M. Valença, 2 Rodrigo Duquia, 2 and Manuel A. P. Vilela 1,2 1 Institute of Cardiology/University Cardiology Foundation and Post-Graduation Program, Ivo Corrˆ ea-Meyer Institute of Ophthalmology, Porto Alegre-RS, Brazil 2 Federal University of Health Sciences of Porto Alegre, Brazil Correspondence should be addressed to Manuel A. P. Vilela; mapvilela@gmail.com Received 12 November 2018; Accepted 8 January 2019; Published 20 January 2019 Academic Editor: Alireza Firooz Copyright © 2019 Carina G. Colossi et al. Tis is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Background. Ophthalmic fndings in mycosis fungoides (MF) can be highly variable. It seems that the prevalence of ophthalmic fndings could be much more common than previously assumed. Objective. To present case series examined in the last 12 months, together with a literature review. Methods. Symptomatic patients with biopsy-proven mycosis fungoides were examined ophthalmologically in a 12-month period. Te medical records of afected patients were reviewed. Results. Eight patients were examined. Of these, 75% were male, all were Caucasian, and average age was 58.2 years. Blepharitis (50.0%), thickened eyelids (37.5%), and faking (25.0%) were the most prevalent fndings. Conclusion. Incidence of MF afecting the eyes and surrounding structures may be greater than estimated. Early case management ofers means to reduce difculties experienced with later diagnosis. Regular monitoring by an ophthalmologist is justifed, including that of asymptomatic cases. 1. Introduction Mycosis fungoides (MF) is a rare primary T-cell cutaneous lymphoma. Its annual estimated incidence is 6.4-9.6 cases per one million inhabitants in the USA [1–3]. Clinical diagnosis is usually difcult, especially at early stages. Diagnosis ofen requires multiple biopsies and is commonly performed quite late, given its similarities with other conditions and the scarcity of typical clinical or histopathologic signs [2–5]. Blotches or faking erythematous plaques are usually the initial manifestation, making the condition similar to other skin disorders such as eczemas, atopic dermatitis, psoriasis, and pityriasis lichenoides. In the next stage infltrative lesions appear as the disease progresses. Following this, tumorous lesions appear and lymph nodes and other organs are afected. It is a disease mostly afecting White adults. As a rule the disease is indolent and controllable. Available treatment is for the most part palliative, although it is free from risks and serious side efects and improves long-term control and survival [1–5]. Bone marrow transplant is the only treatment that cures the disease but is rarely adopted [6, 7]. MF involving the eyes and their surrounding structures is considered to be rare (2% of afected cases) and is probably underestimated owing to difculties in diagnosing it in the early stages [1]. Only three sizeable series can be found in the accounts available in the literature. Among the 30 patients described by Stenson & Ramsay [8], 36.7% had ophthalmological changes and eyelid tumours were the most common fnding (26.7%). Leib et al. [9] described 17 cases and eyelids were the most frequently afected region by blepharitis or ectropion. Cook et al. [10] assessed 210 cases, whereby the most prevalent condition was ectropion (40.4%). Our aim is to present case series examined over the last 12 months, to review the literature, updating manifestation in the eyes and their surrounding structures, as well as possibilities for case management. Hindawi Case Reports in Dermatological Medicine Volume 2019, Article ID 2380598, 4 pages https://doi.org/10.1155/2019/2380598