INTERNATIONAL JOURNAL FOR RESEARCH IN EMERGING SCIENCE AND TECHNOLOGY, VOLUME-2, ISSUE-9, SEP-2015 E-ISSN: 2349-7610 VOLUME-2, ISSUE-9, SEP-2015 COPYRIGHT © 2015 IJREST, ALL RIGHT RESERVED 19 Haemato- Biochemical Analysis of Goats Naturally Infected with Peste Des Petits Ruminants Sutopa Das 1 , Rita Nath 2 , V Balamurugan 3 , R Choudhury 4 and M.Devi 5 1 Associate Professor, Department of Microbiology / College of veterinary Science/Assam Agricultural University, Guwahati/Assam/India 1 d_sutopa@yahoo.com 2 Associate Professor, Department of Biochemistry/ College of Veterinary Science/Assam Agricultural University, Guwahati/Assam/India 2 ritasankr@rediffmail.com 3 Department/ Organization/ University, Address Including Country Name 3 balavirol@gmail.com 4 Research Scholar/ Department of Microbiology / College of veterinary Science/Assam Agricultural University, Guwahati/Assam/India 4 choudhuryraka@gmail.com 5 Research Scholar/ Department of Microbiology / College of veterinary Science/Assam Agricultural University, Guwahati/Assam/India 5 maitrayeee@gmail.com ABSTRACT The study was aimed to examine the haematological and biochemical profile of goats naturally infected with Peste des petits ruminant (PPR) .Severe disease was recorded in few villages of Kamrup and Nalbari districts of Assam affecting large population of goats causing death in many animals due to diarrhoea. Serum samples were taken from 15 animals showing clinical signs of PPRV infection (infected group) for haematological and biochemical analysis. In addition, 10 numbers of sera samples were also examined from apparently healthy animals (control group). Presence of antibodies against PPR virus was determined using competitive enzyme linked immunosorbet assay (c-ELISA). Haematological and biochemical analysis of blood profile of PPR positive serum samples (n=15) as well as control (n=10) were performed.Among the haematological parameters Hb, RBC and PCV showed a significant (P<0.05) decrease while WBC, both Absolute and Relative Monocyte and relative lymphocyte showed a significantly (P<0.05) increase in PPR infected group than those of control group. Among the biochemical parameters,it was observed that there was a statistically significant (P<0.01) increase in creatinine and bilirubin and a significant decrease (P<0.01) in glucose, protein, albumin, A-G ratio in infected goats compared to those of control group.Results of the present study indicated that infection with PPR in goats provide valuable datas about the haematological and biochemical findings and also clarifies the pathogenesis of PPR infection Keywords —Blood Chemical Analysis, Antibodies, Peste Des Petits Ruminants, Competitive Enzyme Linked Immunosorbet Assay, Goats. 1. INTRODUCTION Peste des petits ruminant (PPR) is currently an emerging, economically important transboundary and notifiable World Organization for Animal Health (OIE) viral disease of sheep and goats. The disease is highly contagious and characterized by pyrexia, ocular and nasal discharges, necrotizing and erosive stomatitis, enteritis, diarrhoea and bronchopneumonia, followed by either death or recovery from the disease [1].