Topic C2: New chemical substances in buildings ECOS-POUSS: A NATIONWIDE SURVEY OF SEMI-VOLATILE ORGANIC COMPOUNDS IN HOME SETTLED DUST Corinne MANDIN 1,2,3,* , Fabien MERCIER 2,3,4 , Jean-Paul LUCAS 1 , Olivier RAMALHO 1 , Olivier BLANCHARD 2,4 , Nathalie BONVALLOT 2,4 , Gaëlle RAFFY 2,3,4 , Erwann GILLES 2,3,4 , Philippe GLORENNEC 2,4 , and Barbara Le BOT 2,3,4 1 University Paris-Est, Scientific and Technical Centre for Building (CSTB) / Observatory of Indoor Air Quality, Marne-la-Vallée, France 2 INSERM-U1085, IRSET-Research Institute for Environmental and Occupational Health, Rennes, France 3 LERES-Environment and Health Research Laboratory (IRSET and EHESP Technologic Platform), Rennes, France 4 EHESP-School of Public Health, Sorbonne Paris Cité, Rennes, France * Corresponding email: corinne.mandin@cstb.fr Keywords: SVOC, Dwelling, Phthalate, PBDE, PCB SUMMARY Forty-eight SVOCs, e.g. phthalates, polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs), polycyclic aromatic hydrocarbons (PAHs), pyrethroids, organochlorine and organophosphorous pesticides, synthetic musks, and tributylphosphate, were measured in home settled dust collected from household vacuum cleaner bags. Thirty- two compounds were detected in more than half of the dwellings. Permethrin and bisphenol-A concentrations appeared to be higher in France in comparison to other countries. INTRODUCTION Semi-volatile organic compounds (SVOCs) are of concern due to their known or suspected health effects and due to the widespread exposure through different environmental media and pathways (Weschler and Nazaroff, 2008). The objective of this study was to assess the SVOC concentrations in household settled dust at a nationwide scale. Vacuum cleaner bags were collected across mainland France in 300 dwellings occupied by at least one child aged 6 months to 6 years. The sampling design made it possible to extrapolate the measured concentrations to the population of French dwellings occupied by these children. METHODOLOGIES Target compounds The target SVOCs were selected using a ranking method based on toxicity and indoor exposure levels. A literature review provided, for each target SVOC, data on its frequency of detection and reported concentrations in home settled dust, primarily in France or by default in other countries. On the other hand, the toxicity reference doses were retrieved from toxicity databases or were calculated from No Observed Effect Levels (or Lowest Observed Effect Levels) and uncertainty factors. Ranking scores were calculated (Bonvallot et al., 2010).