Research Article Determinants of Higher-Risk Sexual Behavior in Some Selected African Countries Adikwor Ewoenam Puplampu, 1 Seth Afagbedzi, 1 Samuel Dery, 1 Dzifa Adimle Puplampu, 2 and Chris Guure 1 1 Department of Biostatistics, School of Public Health, University of Ghana, Legon, Accra, Ghana 2 Center for Climate Change and Sustainable Studies, University of Ghana, Legon, Accra, Ghana CorrespondenceshouldbeaddressedtoChrisGuure;cbguure@ug.edu.gh Received 5 July 2021; Accepted 24 August 2021; Published 6 September 2021 AcademicEditor:Jos´ eA.Castro Copyright©2021AdikworEwoenamPuplampuetal.isisanopenaccessarticledistributedundertheCreativeCommons AttributionLicense,whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkis properly cited. Background.Althoughhigher-risksexualbehavior(H-RSB)isamajorcontributortotherapidrisingrateofnewHIVinfections, thereexistspaucityofcomprehensiveevidenceacrossthesub-SaharanAfricanregion.epurposeofthisstudywastodetermine theprevalenceofH-RSBanditsdeterminantsacrosssub-SaharanAfricatoinformpolicy. Method.Datawereobtainedfromthe DemographicandHealthSurvey(DHS)oftensub-SaharanAfrican(SSA)countrieswiththeirthreemostcurrentDHSsurveys from 2000 to 2016. Only participants who ever had sexual encounters in their lifetime were included in the study. Weighted adjustedCoxregressionwithrobustvarianceandconstanttimewasusedtoinvestigatedisparitiesofH-RSBamongthetenSSA countries. Relationships between sociodemographic, socioeconomic, knowledge, mass media, and H-RSB were investigated. Results. e trend and prevalence of higher-risk sexual behavior show that Lesotho experienced a decreasing trend of the prevalenceofH-RSBfrom8.92inperiodoneto6.42inperiodthree.Ghanaexperiencedamarginalincreasefrom6.22inperiod oneto6.76inperiodtwoandthento6.43inthethirdperiod.However,Malawi,Zambia,andZimbabweobtainedamarginal increasingtrendintheprevalenceofH-RSBfromperiodonetothree:2.75to3.74,4.33to6.24,and6.11to7.99,respectively. Meanwhile,theprevalenceofH-RSBinNamibiaandUgandadecreasedinperiodtwoto1.84and5.76butincreasedinperiod threeto2.01and6.83,respectively.Generally,determinantsofH-RSBamongthecountriesincludeage,sex,religiousaffiliation, marital status, educational level, employment status, economic status, age at first sex, and status of circumcision. Conclusion. TrendofrelativelyhighprevalenceofH-RSBhasbeenfoundacrossmajorityofthecountrieswithkeysociodemographicfactors influencingH-RSB.erefore,differenttargetedinterventionalapproachesareneededinallthecountriestohelpreduceH-RSB andtheoverallHIVincidence.Ifissuesregardingsexualbehaviorandsexualhealtharenotaddressedadequately,H-RSBcan negate all the appreciable efforts aimed at ending the HIV pandemic by 2030. 1. Introduction Sub-Saharan Africa is home to an estimated 12% of the worldwidepopulationyetaccountsformorethan70%ofthe globalburdenofHIVinfections[1,2].eadultprevalence ofHIVintheregionishighcomparedtootherregionsofthe globe.In2014,70%oftheinfectionsintheworldand66%of newinfectionsanddeathsrelatedtoHIVeachoccurredin the subregion [1]. Again in 2017, an estimated 71% of the world’sinfections,65%ofnewinfections,and75%ofdeaths relatedtoAIDSwererecordedintheregion[3].ereexists asignificantdifferenceintheseverityoftheepidemicwithin the subregion [4]. ere is also an association between geographical distributions and the spread of the HIV epi- demicinsomepartsoftheregion[5].Althoughmostofthe countriesintheregionshareaconsiderablenumberofthe epidemiologic attributes, substantial subregional variation exists in the severity of these epidemics [6]. Adult HIV prevalence is generally highest (>10%) in Southern Africa, intermediateinCentralandEastAfrica,andlower(<5%)in West Africa. e trends in new HIV infections across countries in SSA have shown a decline by more than 33% Hindawi Scientifica Volume 2021, Article ID 8089293, 13 pages https://doi.org/10.1155/2021/8089293