Health, 2016, 8, 363-369 Published Online February 2016 in SciRes. http://www.scirp.org/journal/health http://dx.doi.org/10.4236/health.2016.84038 How to cite this paper: Nourizadeh, M., Shakeri, M., Mousavi, S.S.B., Adel, M.H., Najafi, M.H., Rezaee, Z., Nourizadeh, M. and Nourizadeh, S. (2016) Study the Effect of High Dialysate Potassium Solution in Comparison to Low Potassium Dialysate Solution in End Stage Renal Disease Patients. Health, 8, 363-369. http://dx.doi.org/10.4236/health.2016.84038 Study the Effect of High Dialysate Potassium Solution in Comparison to Low Potassium Dialysate Solution in End Stage Renal Disease Patients Mohammad Nourizadeh 1* , Masih Shakeri 1 , Seyed Seifolah Beladi Mousavi 1 , Mohammad Hassan Adel 1 , Mohammad Hossein Najafi 1 , Zahra Rezaee 1 , Mehdi Nourizadeh 1 , Sara Nourizadeh 2 1 Atherosclerosis Research Centre, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran 2 Department of Cell & Molecular Biology, Faculty of Biological Sciences, Kharazmi University, Tehran, Iran Received 18 December 2015; accepted 26 February 2016; published 29 February 2016 Copyright © 2016 by authors and Scientific Research Publishing Inc. This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/ Abstract Background: Nowadays cardiovascular diseases remain as the single most common cause of death in chronic dialysis patients; the aim of this study was to evaluate the effects of two different regi- mens of dialysis potassium removal in patients with a tendency to develop arrhythmias during haemodialysis (HD). Methods and Materials: There were 88 (36 men and 52 women) end stage renal disease (ESRD) patients recruited for the study. They received regular haemodialysis three times per week at the haemodialysis units of a university medical centre (Golestan hospital) dur- ing year 2011. We compared the arrhythmogenic effects of two dialysis techniques. Results: There was a tendency in the HD solution with constant (3 mEq/l) K for premature ventricular complex (PVC) appearance in to be reduced as compared with constant (2 mEq/l) K in the time of dialysis period, although this reduction was not statistically significant(P = 0.09). There was a significant reduction in SVC in the HD solution with constant (3 mEq/l) K as compared with constant (2 mEq/l) K. Discussion: In conclusion, the use of a model of intra-HD potassium that is more close to potas- sium serum concentration of ESRD patients can reduce the arrhythmogenic effect of HD in patients on regular HD treatment. Keywords Arrhythmia, Dialysis, End Stage Renal Disease * Corresponding author.