Fast Statistical Alignment: Text S1 1 Fast Statistical Alignment: Text S1 Robert K. Bradley 1,* , Adam Roberts 2 , Michael Smoot 3 , Sudeep Juvekar 2 , Jaeyoung Do 4 , Colin Dewey 4,5 , Ian Holmes 6 , Lior Pachter 1 1 Department of Mathematics and Department of Molecular & Cellular Biology, University of California, Berkeley, CA 94720, USA 2 Department of EECS, University of California, Berkeley, CA 94720, USA 3 Department of Bioengineering, University of California, San Diego, CA 92093, USA 4 Department of Computer Sciences, University of Wisconsin, Madison, WI 53706, USA 5 Department of Biostatistics & Medical Informatics, University of Wisconsin, Madison, WI 53706, USA 6 Department of Bioengineering, University of California, Berkeley, CA 94720, USA * E-mail: rbradley@berkeley.edu