Badea et al. Medicamentul Veterinar / Veterinary Drug Vol. 9(1). May - June 2015 48 The efficacy of 30% FENBENDAZOLE anthelmintic paste in cyathostominosis in horses Eficacitatea pastei antihelmintice FENBENDAZOL 30% în ciatostominoza cabalinelor Corina Badea, Florin Ş. Hora, Sorin Morariu, Gheorghe Dărăbuş Faculty of Veterinary Medicine, Department of Parasitology, Timișoara, Romania Correspondance: cori.badea@yahoo.com Key words: Horses, cyathostomins, FECRT. Cuvinte cheie: Cai, ciatostomine, FECRT. Abstract Horse cyathostominosis is a large intestine helminthosis caused by parasites belonging to the family Strongylidae, subfamily Cyathostominae. The cyathostomins (small strongyles) represent a challenge for the parasitologists and animal owners due to the different ontogenesis, the high number of parasite species and their ability to develop anthelmintic resistance. The faeces were examined by flotation (Willis) method and the infestation level was determined by McMaster method in day 0, 7 and 14 post treatments. The product Vanbendazol (30% fenbendazole) had a 97.7% efficacy in the treated horses from Şofronea, Arad County, using the Faecal egg count reduction test (FECRT). Also were performed Presidente and Borgsteede relations and the anthelmintic efficacy was 98.2% for the both relations. Rezumat Ciatostominoza cabalinelor este o helmintoză a intestinului gros produsă de paraziți din familia Strongylidae, subfamilia Cyathostominae. Ciatostominele (strongili nemigratori) reprezintă o provocare atât pentru parazitologi cât și pentru proprietarii de animale datorită ontogenezei variabile, numărului mare de specii și al abilității lor de a dezvolta chimiorezistență. Fecalele au fost examinate prin metoda flotației (Wllis), iar în zilele 0, 7 și 14 post tratament a fost determinat nivelul infestației prin metoda McMaster. Eficacitatea produsului Vanbendazol (fenbendazol 30%) a fost de 97,7% în urma deparazitării cabalinelor din Șofronea, județul Arad, determinată prin testul reducerii numărului de ouă din fecale (FECRT). De asemenea a fost determinată și prin relațiile Presidente și Borgsteede, iar în ambele relații eficacitatea a fost de 98,2%. Introduction Cyathostomins are considered to be the most pathogenic group of strongyles in equids worldwide, due to decline of large strongyles Strongylus sp. [1, 4, 5, 7, 11, 12, 13]. Horse cyathostominosis is a large intestine helminthosis caused by parasites belonging to the family Strongylidae, subfamily Cyathostominae, which consist in 14 genera and 50 species. The parasitized horses present clinical signs like: weight loss, colic, diarrhea, protein losing enteropathy and in severe infestation death. The parasitosis can occur in horses either in grazing or in stables [3] causing a high morbidity and mortality in horses [5, 6]. The incorrect dosage and frequently administration of the same substance can lead to a anthelmintic resistance. Benzimidazole resistance in cyathostomins is widespread [1, 2, 8, 9, 10, 15]. The aim of the study was to find out the efficacy of 30% Fenbendazol (FBZ) in the infestation with cyathostomins in horses.