Revista de Chimie https://revistadechimie.ro https://doi.org/10.37358/Rev. Chim.1949 Rev. Chim., 71 (312-319), 2020, 312 https://doi.org/10.37358/RC.20.3.8003 Accidental Exposure to Blood and Biological Products in a Tertiary Teaching Hospital in Romania ERZSEBET KALMAN 1,2* , AMANDA RADULESCU 3 , ANDREEA HANGANUT 3 , CRISTINA BORZAN 1 1 Iuliu Hatieganu University of Medicine and Pharmacy, Faculty of Medicine, Public Health and Management Department, 8 Victor Babes Str., 400012, Cluj-Napoca, Romania 2 Regional Institute of Gastroenterology and Hepatology Prof. Dr. Octavian Fodor, 5 Constanta Str., 400158, Cluj-Napoca, Romania 3 Iuliu Hatieganu University of Medicine and Pharmacy, Faculty of Medicine, Epidemiology Department, 8 Victor Babes Str., 400012, Cluj-Napoca, Romania Abstract. Disclosure of the announcement rate of occupational exposure to blood and other biological fluids and the compliance rate for post exposure prophylaxis and monitoring measures among employees of the Regional Institute of Gastroenterology-Hepatology ”Prof. Dr. Octavian Fodor” Cluj-Napoca. A prospective study was conducted between 2011-2016. All the hospital employees were included in the study. Descriptive analysis of reported cases of exposure to biological products was performed. Considering the number of employees and professional categories throughout the years of study, there was reported a very small number of accidents due to biological sample exposure, compared to statistical data. We have assessed the compliance of the exposed medical staff to post- exposure monitoring protocol, which was very low. Keywords: exposure reporting, biological products, health care workers, compliance, HBs post-vaccine antibodies 1.Introduction This study is part of a PhD research with the title of ”The study of production conditions and the predisposing factors in the accident with exposure to biological products of healthcare personnel”. The HCW could be exposed to blood and other biological products from the assisted patients during performing their professional activity. These occupational exposures should be reported in order to apply the post-exposure prophylaxis, necessary to minimize the transmission risk for bloodborne pathogens like hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV). Our first assumption was the existence of a sub-reporting among the health care workers (HCW) of different occupational exposure to blood and other biological products. A low compliance for post-exposure prophylaxis measures was also observed [1-3]. Moreover, these undesirable events should advocate for the employers to implement the use of sharp objects (needles, scalpels) fitted with a protective system [6, 9]. Our second assumption was the fact that the anti-hepatitis B vaccine offers protection (protective level of antibodies ≥10 mIU/mL) to ≥90% of those vaccinated. 2.Materials and methods The study was conducted for a period of 6 years, between 2011-2016 and led to the database fulfillment of the Health Care Associated Infections Prevention and Control Department in ”Prof. Dr Octavian Fodor ”Regional Institute of Gastroenterology - Hepatology, Cluj - Napoca, Romania (universitary tertiary hospital with 410 beds, a mean of 17700 hospital admissions per year and a mean of 856 employees per year). The data was collected in a prospective longitudinal way by recording *email: elikalman@yahoo.com