~ 1 ~ Journal of Medicinal Plants Studies 2017; 5(5): 01-03 ISSN (E): 2320-3862 ISSN (P): 2394-0530 NAAS Rating 2017: 3.53 JMPS 2017; 5(5): 01-03 © 2017 JMPS Received: 01-07-2017 Accepted: 02-08-2017 Mohd Shamim Akhtar Assistant Professor, Dept. of Mahiyatul Amraz, Govt. Tibbi College and Hospital, Patna, Bihar, India Mohd Aleemuddin Quamri Assistant Professor, Dept. of Moalejat, National Institute of Unani Medicine, Bangaluru. MA Siddiqui Director, National Institute of Unani Medicine, Bangaluru. Rajesh Research Officer (U) Scientist L1, Regional Research Institute of Unani Medicine, Patna, Under CCRUM New Delhi. Correspondence Mohd Shamim Akhtar Assistant Professor, Dept. of Mahiyatul Amraz, Govt. Tibbi College and Hospital, Patna, Bihar, India Clinical study on Ibtedai Sehar (Primary Insomnia) with therapeutic evaluation of Roghan Kaddu and Safoofe Kahu Mohd Shamim Akhtar, Mohd Aleemuddin Quamri, MA Siddiqui and Rajesh Abstract Sleep is one of the basic necessities of life such as air food and water etc for every animal species from insects to mammals. Sehar (Insomnia) is described as sleeplessness and its causes considered as yaboosate sada or yaboosate maddi saudavi, hararat wa yaboosat sada or maddi safravi, accumulation of rutubate shor in brain, plethora of body with waste humours, mal digestion, acute fevers and their toxic irritable vapours, acute sadness, apprehensions, and phobias etc. Sehar has been classified into Sehar Yabis, Sehar Rutubi, and others. This study was a single blind to evaluate the efficacy and safety of Unani formulation (Roghan Kaddu, Safoof Kahu) in Ibtedai Sehar (Primary Insomnia. The test drug Roghan Kaddu: 5 ml for local application over the scalp and Sofoof Kahu: 5 grams oral administration at night for 15 days. The data was analyzed statistically used repeated measure Anova test and using the student t-test (paired). The test drug was found significantly effective in both subjective and objective parameters. Hence, it can be concluded that the test drugs are safe and effective. Keywords: Ibtedai Sehar (Primary Insomnia), Roghan Kaddu, Safoof Kahu 1. Introduction According to Unani Doctrine sleep and awakening (Naum wa yequza) is one of the six essential factor of life (Asbaab sitta zarooria) which are dormitorily working throughout the life [1] . According to Avicenna, sleep directs the Hararate Gharizia (Innate heat) inwards and strengthens the physical faculty. It takes up the digestion and maturation of food and converts it into blood. Whilst wakefulness has the opposite effect to that of sleep. If wakefulness predominates resultant in causing disturbance in brain by producing dryness and weakness, leading to insomnia and confusion [2] . Sehar (Insomnia) is described as sleeplessness and its causes considered as yaboosate sada or yaboosate maddi saudavi, hararat wa yaboosat sada or maddi safravi, accumulation of rutubate shor in brain, plethora of body with waste humours, mal digestion, acute fevers and their toxic irritable vapours, acute sadness, apprehensions, and phobias etc. Sehar has been classified into Sehar Yabis, Sehar Rutubi, and others [4, 5] . An insomnia complaint lasting one to several nights (within a single episode) is termed as transient insomnia. It is typically the result of situational stress or a change in sleep schedule or environment. Insomnia lasts from few days to 3 weeks is termed as short-term insomnia. It is usually associated with more protracted stress such as recovery from surgery or short-term illness. Chronic insomnia lasts from months to years. Various causes of insomnia are described in modern medicine such as stress, severe pain, change in the sleep environment, vigorous exercise or hot showers before sleep, caffeine, aging, use of glucocorticoids, asthma etc [3] . The clinical features are sleeplessness, dryness, irritability of moods, burning sensation in eyes, thirst, fatigue, and drowsiness etc [2] . Based on the etiology of the disease it has been treated accordingly by using Murattib Tila, Nutool, Roghan, Majoon, Safoof, and Sheerajat etc [5] . Promoting sleep in natural way reduces the used for medication with sedation [6] . Avicenna suggests that an applying Roghan Kaddu (Lagenaria siceraria) on forehead and temporal regions will helps in promoting sleep. [2] Jalinoos prescribed and used Kahu (Lactuca sativa Linn.) to induce sleep [5] .