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The Pharma Innovation Journal 2018; 7(12): 235-237
ISSN (E): 2277- 7695
ISSN (P): 2349-8242
NAAS Rating: 5.03
TPI 2018; 7(12): 235-237
© 2018 TPI
www.thepharmajournal.com
Received: 14-10-2018
Accepted: 15-11-2018
Sazid Alam
PG Scholars, Dept. of Moalajat,
LUMCH & Research Centre,
Bijapur, Karnataka, India
Md. Anzar Alam
Ph D Scholar, Dept. of Moalajat,
NIUM, Bangalore, Karnataka,
India
Khalid Eqbal
PG Scholars, Dept. of Moalajat,
LUMCH & Research Centre,
Bijapur, Karnataka, India
Mohd Aleemuddin Quamri
Reader, Dept of Moalajat,
NIUM, Bangalore, Karnataka,
India
Ghulamuddin Sofi
Reader, Dept of Ilmul Advia,
NIUM, Bangalore, Karnataka,
India
Correspondence
Sazid Alam
PG Scholars, Dept. of Moalajat,
LUMCH & Research Centre,
Bijapur, Karnataka, India
Approach of understanding dyslipidaemia in unani
medicine
Sazid Alam, Md. Anzar Alam, Khalid Eqbal, Mohd Aleemuddin Quamri and
Ghulamuddin Sofi
Abstract
Dyslipidaemia is a common metabolic disorder which is a major cause of coronary heart disease. It
affects both genders, but is more common among males. In India 25-30% of urban and 15-20% rural
subjects are suffering from dyslipidaemia.Currently, various synthetic lipid lowering agents are being
used, however, Long term use of these medicine may leads to various adverse effects like hepatotoxicity,
dyspepsia, myopathy, bloating, constipation, renal dysfunction etc. present study indertakes the concept
of dyslipidemia as understtod in Unani mdicinee.
Keywords: Dyslipidaemia, unani medicine, obesity
Introduction
Dyslipidaemia is a disorder of lipoprotein metabolism, which includes over production or
deficiency of lipoproteins or both. It can manifest as an elevation of plasma cholesterol,
triglycerides, or both, or a low high density lipoprotein level or all three together that
contributes to the development of atherosclerosis
[1]
.
Dyslipidaemia is a major contributor to cardiovascular morbidity and mortality. Although
awareness of the importance of the risk of dyslipidaemia has increased, however, its treatment
has not improved accordingly. Even though the actual number of individuals receiving
treatment has increased, the proportion of those who are treated but did not reach the
recommended treatment goal is still disturbing
[2]
.
Gupta R et al (2017) reported that Dyslipidaemia is the most important atherosclerotic risk
factor. Recent studies have reported that high cholesterol is present in 25-30% of urban and
15–20% rural subjects. This prevalence is lower than high-income countries. The most
common Dyslipidaemia in India are borderline high LDL cholesterol, low HDL cholesterol
and high triglycerides. Studies have reported that over a 20-year period, total cholesterol, LDL
cholesterol and triglyceride levels have increased among urban populations. Case-control
studies have reported that there is significant association of coronary events with raised
apolipoprotein B, total cholesterol, LDL cholesterol and non-HDL cholesterol and inverse
association with high apolipoprotein A and HDL cholesterol. Prevalence of suspected familial
hypercholesterolemia in urban subjects varies from 1:125 to 1:450. Only limited studies exist
regarding lipid abnormalities in children. There is low awareness, treatment and control of
hypercholesterolemia in India
[3, 4, 5]
.
Rasheed et al (2014) reported that prevalence of Dyslipidaemia varies according to the age,
sex, race, geographical conditions and association with other diseases. The age group of 30 to
40 years has tendency to high prevalence, but above 60 years it become markedly high. Men
are more prone to dyslipidaemic than women; rural population has less prevalence then urban
in India. The prevalence with other disease association is high i.e. diabetes, obesity, renal
disease and liver disease etc
[6]
.
Dyslipidaemia is anoutcome of shifting from rural to urban that leads to sedentary lifestyle so
the prevalence of Dyslipidaemia is higher in urban than rural areas
[7]
.
There are several risk factor associated with Dyslipidaemiaviz; diabetes, obesity, hypertension,
hypothyroidism, sedentary life style, fatty/oily diets, excess alcohol intake, smoking
[8]
.
Untreated dyslipidaemia leads to co-morbid symptoms (tiredness, dyspnoea, lethargy, loss of
appetite, weight gain, PCOD) and complication (hypertension, hypothyroidism, infertility,
PCOD, atherosclerosis, coronary artery disease, cardiovascular Death)
[9]
.
In Classical Unani literature, there is a concept of Quwt-e-Tabaiyah, which provides the
functions of Taghziya (nutrition), Namiya (growth) and Tanasuliya (reproduction) in the body,