Elsayed et al. Res Rep Oral Maxillofac Surg 2018, 2:009 Volume 2 | Issue 1 Open Access • Page 1 of 10 • Citaton: Elsayed NA, El-Wegoud MA, Aziz OMA, Nabhan AF, Helmy ES (2018) Trigger Point Deactva- ton in Muscles of Mastcaton in Myofascial Pain Dysfuncton (MPD) Patents: A Qualitatve Systemat- ic Review. Res Rep Oral Maxillofac Surg 2:009. Accepted: August 25, 2018; Published: August 27, 2018 Copyright: © 2018 Elsayed NA, et al. This is an open-access artcle distributed under the terms of the Creatve Commons Atributon License, which permits unrestricted use, distributon, and reproducton in any medium, provided the original author and source are credited. Elsayed et al. Res Rep Oral Maxillofac Surg 2018, 2:009 ISSN: 2643-3907 Research Reports in Oral and Maxillofacial Surgery Trigger Point Deactvaton in Muscles of Mastcaton in Myofascial Pain Dysfuncton (MPD) Patents: A Qualitatve Systematc Review Nagwan A Elsayed 1* , Marwah Anas El-Wegoud 2 , Omniya M Abdel Aziz 1 , Ashraf F Nabhan 3 and Emad S Helmy 1 1 Department of Oral and Maxillofacial Surgery, Cairo University, Egypt 2 Egyptan Center for Evidence Based Medicine (ECEBM), Egypt 3 Department of Obstetrics and Gynaecology, Ain Shams University, Egypt *Corresponding author: Nagwan A Elsayed, MSc, Faculty of Oral and Dental Medicine, Department of Oral and Maxillofacial Surgery, Cairo University, Hadayeq El Qubba, Cairo, Egypt, Tel: +20-0111-8489-627 Introducton Descripton of the conditon Myofascial pain dysfuncton (MPD) is a conditon afects both muscles and fascia. It is characterized by painful points called trigger points, which may be single or multple within taut muscle bands. It is also associat- ed with local twitch response when stmulated by pres- sure or needling generatng referred pain to a partcular patern. It is frequently accompanied by headache and limited mouth opening [1-4]. Studies that are conduct- ed in pain management have shown high prevalence of MPD in patents presentng with regional pain, ranging from 30% to 93% [5-9] aged from 30 to 50-years-old [3] and in women [8]. The actual cause of MPD is stll unknown but there are a number of precipitatng fac- REviEW ARticlE Check for updates Abstract Background: Myofascial Pain Dysfunction (MPD) is a re- gional muscular pain characterized by the presence of trig- ger points (TrPs), which are painful points cause referred pain when stimulated. There are many treatment modalities for MPD. However, no treatment has proved its superiority over the others yet. Objectives: To fgure out what is the most effective treat- ment in relieving pain in patients with myofascial pain dys- function (MPD) among local anesthesia, botox and trigger point dry needling. Methods: We conducted the review according to the Cochrane methods. We searched the Cochrane Oral Health Group Trial register, Cochrane Central Register of Con- trolled Trials, MEDLINE, the WHO International Clinical Tri- al Registry Platform for ongoing studies (30 June 2018) and hand searched citation lists of relevant publications. Two review authors assessed trials for inclusion, risk of bias, ex- tracted data, and checked for accuracy. We have expressed results as risk ratio or mean differences (MD), together with their 95% confdence intervals (CI). Results: We included 2 trials of 3 reports (65 participants). One trial reported pain relief immediately after injection of local anesthesia and dry needling (MD -7.00, 95% CI -32.02 to 18.02). No meta-analysis was conducted because of lack of data. Conclusion: There is insuffcient evidence to support the superiority of one intervention over the others or no differ- ence among them in the treatment of MPD of muscles of mastication. Keywords Myofascial pain syndrome, Botox, Local anaesthesia, Dry needling Abbreviations MPD: Myofascial Pain Dysfunction; MTrPs: Myofascial Trig- ger Points; WHO: World Health Organization; DN: Dry Nee- dling; TDN: Trigger Point Dry Needling; SEA: Spontaneous Electrical Activity; LTR: Local Twitch Response; CGRP: Calcitonin Gene Related Peptide; SP: Substance P; TMD: Temporomandibular Disorder; RCTs: Randomized Con- trolled Trials; VAS: Visual Analogue Scale; NHP: Notting- ham Health Profle