DOI: 10.21276/sjams.2016.4.7.9 2353 Scholars Journal of Applied Medical Sciences (SJAMS) ISSN 2320-6691 (Online) Sch. J. App. Med. Sci., 2016; 4(7A):2353-2356 ISSN 2347-954X (Print) ©Scholars Academic and Scientific Publisher (An International Publisher for Academic and Scientific Resources) www.saspublisher.com Middle Cerebral Artery Peak Systolic Velocity as a Predictor of Perinatal Outcome in Fetal Growth Restriction Dr. Surbhi Gupta*, Dr. LataRajoria, Dr. Sunitahemanisharma, Dr. Jyotsna Vyas, Dr. Pratibha Agrawal Department of Obstetrics & Gynecology, SMS Medical College & Group of Hospitals, Jaipur, Rajasthan, India, PIN- 302001 *Corresponding author Dr. Surbhi Gupta Abstract: The objective is study the role of fetal MCA-PSV for prediction of perinatal outcome in growth restricted fetuses. A Hospital based cohort study of 40 IUGR fetuses (gestation age 28-36 weeks, EFW < 10 th percentile, UA-PI >95 th percentile) in whom MCA-PSV values were obtained on three or more occasions from the time of admission till delivery depending upon period of gestation and severity of IUGR. MCA-PSV values were considered abnormal when they were above the 95 th percentile for MCA-PSV range. For analysis purpose two groups were made of twenty patients each depending upon MCA-PSV. All the fetuses (100%) in group B (i.e. with abnormal MCA-PSV) had adverse perinatal outcome in the form of either mortality (both IUFD and neonatal mortality) or major neonatal complication consisting of NICU stay ≥ 14 days, requirement of artificial ventilation or presence of intraventricular hemorrhage, respiratory distress or sepsis. Specificity of abnormal MCA-PSV was found to be 100% in predicting adverse perinatal outcome. Doppler study of MCA-PSV should be used in the surveillance of IUGR fetuses together with currently used Doppler parameters so as to decide the optimal time for delivery permitting maximum maturity with minimal fetal hypoxia or acidosis and hence optimizing fetal outcome. Keywords: Fetal growth restriction, Middle cerebral artery- peak systolic velocity, Neonatal-outcome, IUD & NICU stay INTRODUCTION IUGR is considered as a major contributor to perinatal morbidity and mortality, affecting 3-10% of all pregnancies. The timing of delivery of an IUGR baby has always posed a challenge to the obstetrician. It is important to identify the growth restricted fetuses that are at imminent risk of perinatal death from those that are not. This has been made possible by Doppler studies which have become the gold standard in the management of growth restricted fetuses and aids in decision making. Umbilical artery and middle cerebral artery are the most frequently studied vessels and are good predictor of growth restricted fetuses at risk of antenatal compromise[1]. This study aimed to determine the diagnostic performance of fetal MCA-PSV for prediction of adverse perinatal outcome in IUGR fetuses and to determine the longitudinal trends that occur in MCA- PSV in IUGR fetuses. MATERIAL & METHODS This study was a hospital based cohort study done after approval by the Ethics committee. 40 pregnant women with singleton pregnancy with IUGR and who fulfilled the following inclusion criteria were enrolled in the study- Inclusion criteria  Period of gestation 28 weeks and <36 weeks  Estimated fetal weight <10 th percentile &  Umbilical artery- pulsatility index >95 th percentile. Exclusion criteria  Women with fetuses showing congenital anomalies were excluded from the study. Original Research Article