24 24 International Journal of Scientifc Study | November 2018 | Vol 6 | Issue 8 Comparison of Sensorineural Hearing Loss Degree between Controlled and Uncontrolled Type 2 Diabetes Mellitus Patients Ratih Anindita 1 , Adlin Adnan 1 , Delftri Munir 1 , Santi Syafril 2 , Taufk Ashar 3 1 Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, University of Sumatera Utara, Medan, North Sumatera, Indonesia, 2 Department of Internal Medicine, Faculty of Medicine, University of Sumatera Utara, Medan, North Sumatera, Indonesia, 3 Department of Public Health, University of Sumatera Utara, Medan, North Sumatera, Indonesia Macrovascular and microvascular complications of DM have been widely studied. DM can damage nerve cells and blood vessels. Neural networks play an important role in the function of the auditory organs, so DM can also have a negative impact on the hearing organ. It is very possible that there is a relationship between the function of auditory organs and DM because this disease affects organs that are rich in blood vessels such as the cochlea and/or the central nerve including the brain that plays a role in the auditory pathway. Impaired cochlear function can cause hearing loss. [2] The main mechanism of hearing loss in diabetes is associated with microangiopathy in the inner ear. Several studies have concluded the risk of hearing loss in DM. One study in the United States found sensorineural hearing loss that was more frequent in DM patients compared with non-DM. [4] Research in Iran was obtained from 455 patients with DM who had hearing loss as many as 80 patients. In Brazil, it was found that statistically signifcant values increased in patients with DM who had sensorineural INTRODUCTION The relationship between diabetes mellitus (DM) and hearing loss has been debated in recent years. DM prevalence is very high in many countries in the world, and the World Health Organization (WHO) reports that Indonesia ranks the fourth largest in the number of DM patients with a prevalence of 8.6% of the total population after India, China, and the United States. [1] The WHO estimates that the prevalence will increase to 21.3 million in 2030. [1,2] Health research and development agency of the ministry of health in 2013 stated that there was an increase in prevalence in DM patients, which is 1.1% in 2007–1.5% in 2013. [3] Original Article Abstract Objective: The objective of this study was to determine the degree of sensorineural hearing loss in patients with type 2 diabetes mellitus (T2DM) between good and poor glycemic control. Materials and Methods: This was a cross-sectional study of 70 patients with T2DM who admitted between February and May 2018 at Haji Adam Malik General Hospital. Based on examination of hemoglobin A1c (HbA1c), this study will be divided into two groups, good glycemic control (HbA1c <7) and poor glycemic control (HbA1c ≥7), and each group consists of 35 patients. Routine ear, nose, and throat and pure tone audiometry examination were done to know the degree of sensorineural hearing loss. Results: The results of the study showed that the majority in the controlled group of T2DM had normal hearing thresholds compared with the group of uncontrolled T2DM. There was a signifcant difference in proportion of the hearing threshold between controlled and uncontrolled T2DM patients in the right ear (P = 0.004) and the threshold on the left ear (P = 0.008). Conclusion: Uncontrolled T2DM patients are more susceptible to hearing loss. Patients with T2DM are advised to better control of blood sugar levels to prevent hearing loss. Key words: Hemoglobin A1c, Pure tone audiometry, Sensorineural hearing loss, Type 2 diabetes mellitus Access this article online www.ijss-sn.com Month of Submission : 09-2018 Month of Peer Review : 10-2018 Month of Acceptance : 11-2018 Month of Publishing : 11-2018 Corresponding Author: Ratih Anindita, Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, University of Sumatera Utara, Medan, North Sumatera, Indonesia. Phone : +62 81361629876. E-mail: tieh.1701@gmail.com Print ISSN: 2321-6379 Online ISSN: 2321-595X DOI: 10.17354/ijss/2018/298