Pu6fications List of Publications The contents of this thesis include portions of modified text or figures from the following manuscripts: 1) Gowthaman U, Singh V, Zeng W, Jain S, Siddiqui KF, Chodisetti SB, Gurram RK, Parihar P, Gupta P, Gupta UD, Jackson DC, Agrewala JN. "Promiscuous peptide of 16 kDa antigen linked to Pam2Cys protects against M. tuberculosis by evoking enduring memory T cell response" Journal of Infectious Diseases. (2011). (In press). 2) Singh V, Jain S, Gowthaman U, Parihar P, Gupta P, Gupta UD, Agrewala JN. ''Vaccination with infected macrophages supplemented with IL-l +IL-6+TNFa induces long lasting protective memory T cells against Mycobacterium tuberculosis." PLoS One. (2011). 6(l}:e16097. 3) Gowthaman U, Chodisetti SB, Agrewala JN. "T cell help to B cells in germinal centers: putting the jigsaw together". International Reviews in Immunology. (2010). 69:403-20. 4) Singh V, Gowthaman U, Jain S, Parihar P, Banskar S, Gupta P, Gupta UD, Agrewala JN. "Coadministration of interleukins 7 and 15 with bacille Calmette-Guerin mounts enduring T cell memory response against Mycobacterium tuberculosis." Journal of Infectious Diseases. (2010). 202: 480-9. 5) Gowthaman Ut, Chodisetti SBt, Parihar P, Agrewala JN. 2010. "Evaluation of different generic in silico methods for predicting HLA class I binding peptide vaccine candidates using a reverse approach. Amino Acids. 39:1333-42 ('t' equal contribution). 6) Gowthaman U, Agrewala JN. "In silico methods for predicting T cell epitopes: Dr. Jekyll or Mr. Hyde?" Expert Reviews in Proteomics. (2009). 6:527-37. 7) Gowthaman U, Agrewala JN. "In silico tools for predicting peptides binding to HLA class II molecules: more confusion than conclusion" Journal of Proteome Research. (2008). 7:154-63. 8) Chodisetti SBt, Rai PKt, Gowthaman Ut, Pahari S, Agrewala JN "Potential T cell epitopes of Mycobacterium tuberculosis that can instigate molecular mimicry against host: implications in autoimmune pathogenesis" (under review) ('t' equal contribution). 9) Nargis Kt, Gowthaman Ut, Pahari S, Agrewala JN "Manipulation of costimulatory molecules by intracellular pathogens: veni, vidi, vici !f' (under review) ('t' equal contribution). 10) Gowthaman U, Chodisetti SB, Agrewala JN. "Signaling through TLR-2 prevents Th1 cells from exhaustion" (in preparation). 11) Gowthaman U, Rai PK, Agrewala JN. "Alternative vaccination strategies for tuberculosis in endemic areas" (in preparation). vi