3349 International Journal of Medical Science and Clinical Invention, vol. 4, Issue 12, December, 2017 International Journal of Medical Science and Clinical Invention 4(12): 3349-3352, 2017 DOI:10.18535/ijmsci/v4i12.03 ICV 2016: 77.2 e-ISSN:2348-991X, p-ISSN: 2454-9576 © 2017,IJMSCI Original Article Cardiometabolic risk profile in cases of Acute Stroke. Akash Daswaney 1 , Sam Benjamin Rodrigues 1 , Sourya Acharya 2 , Samarth Shukla 3 1 MBBS Student, Primary researchers 2 Professor, Dept. of Medicine 3 Professor, Dept. of Pathology J.N. Medical College,DMIMS (DU) Sawangi (Meghe), Wardha,Maharashtra Address for Correspondence: Dr. Sourya Acharya Professor, Dept. of Medicine,J.N. Medical College,DMIMS (DU),Sawangi (Meghe), Wardha- 442001,Maharashtra Abstract: Aim: To study the cardiometabolic risk profile of acute stroke. Material and Methods: This prospective crossectional study was carried out in Jawarhalal Nehru Medical College AVBR Hospital, which is a 1280 bedded tertiary care hospital situated in Wardha district of Central India. One hundred consecutive cases of acute cerebrovacsular episodes (diagnosed by classical clinical features and confirmed by neuroimaging) who were admitted in the Medicine Ward/ ICU were included in the study. MetS was diagnosed by modified NCEP ATP III criteria. Parameters of cardiometabolic risk factors were compared between stroke patients with metabolic syndrome and without metabolic syndrome. Results: In this study, recurrent stroke occurred significantly in metabolic syndrome group (p<0.05). Individually all metabolic syndrome parameters were associated significantly in acute stroke patients irrespective of the nature of the stroke (ischaemic vs haemorrhagic). When ischaemic and haemorrhagic stroke were separately compared we found no statistically significant correlation between the cardiometabolic risk parameters, suggesting that all the risk factors are distributed equally in both forms of stroke. Conclusion: As the frequency of metabolic syndrome in stroke patients is high. It is important to change the lifestyle in order to prevent cardiovascular diseases and stroke. Keywords: stroke, metabolic syndrome, cardiovascular, cardiometabolic, ischaemia, haemorrhage Introduction : Cerebrovascular diseases are the leading causes of mortality and morbidity in men and women in industrialized countries. [1-3] It is the main reason of functional disability. Stroke is the most common reason of disability affects of more than 700 000 individuals and the third cause of death in the world per year. [2] The consequent post stroke neurologic sequelae remains persistent in 90% patients, one third of the patients suffer permanent disability. [1,2] Cognitive impairment and dementia are the most important post stroke phenomenas. .[3]. Hypertension together with age are leading risk factors for silent or symptomatic cerebrovascular disease. [4-6] The risk of cerebral hemorrhage in hypertensive patients is 3.9 times higher than in non-hypertensive individuals. Dyslipidemia, hypertension and obesity are atherogenic risk factors frequently found in type 2 diabetes patients. All these add to the burden of risk factors for stroke. [7,8] Cigarette smoking is an independent predictor of cerebrovascular disease in both men and women. [9]. Smokers have a relative risk of ischemic stroke of 1.92 times higher as compared to non-smokers. Relationships between dyslipidemia and stroke have not been consistently elucidated. [10] Metabolic syndrome (MetS) is defined (modified NCEP- ATP III) as the presence of three or more of the following: (1) abdominal obesity as determined by waist circumference > 90 cm and > 80 cm for women; (2) triglycerides ≥ 150 mg/dL; (3) HDL cholesterol < 40 mg/dL for men and < 50 mg/dL for women; (4) systolic blood pressure ≥ 130 mm Hg and