This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-Non Commercial- ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. © 2018 Journal of Advanced Pharmacy Education & Research | Published by SPER Publication 108 Effect of health promotion intervention on Nurses’ healthy lifestyle and health-promoting behaviors: RCT study Shokofe Darkhor 1 , Fatemeh Estebsari 2* , Meimanat Hosseini 2 , Jamshid Yazdani Charati 3 , Parvaneh Vasli 2 1 MSc Student in Community Health Nursing, School of Nursing & Midwifery, Shahid Beheshti University of Medical Science, Tehran, Iran, 2 Assistant professor, Department of Community Health Nursing, School of Nursing & Midwifery, Shahid Beheshti University of Medical Science, Tehran, Iran, 3 Associate Professor, Department of Biostatics, Health Sciences Research, Mazandaran University of Medical Science, Sari, Iran. Correspondence: Fatemeh Estebsari, Assistant professor, Department of Community Health Nursing, School of Nursing & Midwifery, Shahid Beheshti University of Medical Science, Tehran, Iran. E_mail: fa_estebsari@yahoo.com ABSTRACT Objectives: Health promoting behaviors (HPBs) are major criteria in determining lifestyle. The present study aimed to investigate the impact of health promotion interventions (HPI) on health-promoting behaviors of nurses. Methods: In this experimental study was conducted in 2016. A total of 100 nurses were randomly selected and divided into two groups of experimental and control. The data was collected using the demographic questionnaire, the Health-Promoting Lifestyle Profile II (HPLP II), the General Self-Efficacy Scale of Schwartz, the Standard Self-Esteem Scale of Rosenberg, and the Brief Self-Control Scale (BSCS) of Tangney. After collecting and analyzing the collected data, the HPI was designed and conducted in 6 sessions for the experimental group. A month and a half after the intervention, the data for both groups were collected and analyzed using SPSS ver 20. Results: Before the HPI, health promoting behaviors, self-efficacy, self-esteem, and self-control had no significant difference among the two groups. After the intervention, the mean scores of health promoting behaviors (p<0.001), self-efficacy (p<0.001), and self-esteem (p<0.001) showed a significant difference between the two groups, but self-control score was not significant (p>0.05). Conclusion: HPI changed HPBs in the nurses, and changes in HPBs will lead to a change in lifestyle. Therefore, it is recommended to use HPI as a comprehensive program to improve and modify lifestyle. Keywords: Health promotion, behavior, intervention, lifestyle, Nurse Introduction Health promoting behavior is a major criterion for determining health and its ultimate goal is to make decisions regarding health and to prepare for desirable behaviors [1] . As an important health factor, health promotion is of the responsibility of individuals and can lead them to higher levels of health [2-4] . Health promoting lifestyle is a multi-causal and multi-dimensional phenomenon which is related to collective patterns of behavior and control, and consistency in doing a series of health-related behaviors is its essence [5] . Self-efficacy belief is a prediction index for a wide range of health behaviors [6] and results in maintaining and improving health behaviors [7] . Self-efficacy refers to confidence and ability of individuals for performing normal behaviors to achieve a healthy lifestyle. People with higher levels of self-efficacy participate more actively in health promotion programs [8] . Self-efficacy in HPBs play a key role in the adoption of preventive behaviors through strengthening individual’s effectiveness, increasing self-confidence, and personal control over the situation [9] . People who believe in the concept of self-efficacy feel that they “can” increase individual control in HPBs through boosting confidence [10] . Studies have shown that self-efficacy strengthens self- esteem which in turn influences motivation. Self-esteem is the main precondition of health through strengthening the Access this article online Website: www.japer.in E-ISSN: 2249-3379 How to cite this article: Shokofe Darkhor, Fatemeh Estebsari, Meimanat Hosseini, Jamshid Yazdani Charati, Parvaneh Vasli. Effect of health promotion intervention on Nurses’ healthy lifestyle and health-promoting behaviors: RCT study. J Adv Pharm Edu Res 2018;8(1):108-114. Source of Support: Nil, Conflict of Interest: None declared.