*Corresponding author: E-mail: alidkhalaji@yahoo.com, ad.khalaji@gu.ac.ir, Department of Chemistry, Faculty of Science, Golestan University, Gorgan, Iran, Tel: +9817 3224 5882; Fax: +9817 3224 5964 Chemical Methodologies 4(2020) 333-339 Chemical Methodologies Journal homepage: http://chemmethod.com Short Communication Preparation and Crystal Structure of N,N΄-bis(2,4- dimethoxybenzylidene)-butane-1,4-diamine Monohydrate Aliakbar Dehno Khalaji Department of Chemistry, Faculty of Science, Golestan University, Gorgan, Iran ARTICLE INFORMATION ABSTRACT Received: 14 April 2019 Received in revised: 28 September 2019 Accepted: 18 December 2019 Available online: 01 May 2020 DOI: 10.33945/SAMI/CHEMM.2020.3.10 In this work, the Schiff-base compound N,N΄-bis(2,4-dimethoxybenzylidene)- butane-1,4-diamine monohydrate ((2,4-MeO-ba)2bn/H2O) was prepared by the condensation reaction of 2,4-dimethoxybenazaldehyde with butane-1,4- diamine in methanol solution and crystallizes as the monohydrate. The crystal structure of (2,4-MeO-ba)2bn/H2O (1) was determined using the X-ray diffraction (XRD) analysis. The compound crystallized in the monoclinic space group C2/c, with a=14.7116 (10), b=15.7333 (9), c=10.2013 (6) Å, β=112.704 (2)° and Z=4. There are one half-molecule and one half of a water molecule in the asymmetric unit, with the (2,4-MeO-ba)2bn molecule completed by inversion symmetry on the midpoint of the central C-C bond of the butane unit and the O atom of the water molecule situated on a twofold rotation axis. Within the imine functionality, the N-C bond lengths of 1.2643 (19) and 1.457 (2) Å were double and single bonds, respectively. Hydrogen bonds of the type O-H∙∙∙N between the water molecule and the imine nitrogen atom of the (2,4- MeO-ba)2bn molecules led to formation of the layers propagating parallel to (100). The 1 H-NMR and FT-IR results confirmed the preparation of this ligand, as well. Copyright © 2020 by SPC (Sami Publishing Company) Chemical Methodologies: http://www.chemmethod.com/ KEYWORDS Schiff-base Condensation reaction Crystal structure Hydrogen bonding Graphical Abstract