International Journal of Innovative Research in Medical Science (IJIRMS) Volume 05, Issue 11, November 2020, https://doi.org/10.23958/ijirms/vol05-i11/1009 www.ijirms.in 572 Original article Oral Cancer Senario in Multiple Centers of Dhaka, Bangladesh Dr. Rajesh Sah 1 , Dr. Mahmuda Akhter *2 1 Oral and Maxillofacial Surgery Department, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 2 Oral and Maxillofacial Surgery Department, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh *Correspondence: Mahmuda Akhter; mahmudanaz@gmail.com Received: 20 November 2020; Accepted: 27 November 2020; Published: 30 November 2020 Abstract Oral cancer is one of the common cancers worldwide and in Bangladesh around 7000 cases are diagnosed yearly. It has variable demographics and patient comes to hospital with different presentations. It is mandatory to know the characteristics of the disease so that better awareness and different treatment modalities can be planned. 162 patients with histopathological diagnosis of oral cancer was include in study by consecutive sampling and characteristics of disease was recorded in scientific data collection sheet which was later analyzed by SPSS and result was presented in table, graph and chart form. Incidence of oral cancer is 56.2% in female, in 59.9% cases buccal mucosa is involved in which 90.1% is squamous cell carcinoma. In Conclusion squamous cell carcinoma is most common oral cancer mainly occurs in buccal mucosa of female, in grade I and stage iii majority of patient present in tertiary centers of Dhaka. Keywords: oral cancer, Bangladesh, squamous cell carcinoma Introduction Oral cancer includes cancers of the lips, tongue, oral cavity, oropharynx, hypopharynx and pyriform sinus [1] . Oral cancer is the 6th most common cancer worldwide [2] . More than 50000 people are diagnosed globally each year and about 30000 mortality annually [3] . The highest prevalence was seen among south Asian population [4] . Approximately 85% to 95% of all oral cancer is squamous cell carcinoma (SCC). However, multiple other malignant lesions can be found in the oral cavity such as sarcoma, minor salivary gland tumors, mucosal melanoma, lymphoma, or metastatic disease from nearly any site in the body [4] . In Bangladesh, more than 7000 new cases are diagnosed per year with mortality is about 6.6% [5] . Cancer is the sixth leading cause of death in Bangladesh (BBS, 2004), according to the Bangladesh Bureau of Statistics. International Agency for Research on cancer (IARC) stated that cancer related death in Bangladesh is 7.5% in 2005 and projected to 13% in 2030. The prevalence of oral cancer in Bangladesh is second and third leading cancer among males and females respectively [6] . Elderly population aged more than 50 years are commonly affected [7] . However, the incidence of oral cancer is increasing mostly among young female population at age less than 45 years [8] . The etiology of oral cancer is multifactorial and smoking with alcohol consumption lead the position among established risk factors. Others established risk factors include tobacco chewing, snuff dipping, betel quid with tobacco like products, exposure to sunlight and radiation, viruses (human papilloma virus and Epstein bar virus), immune deficiency, dentition and ethnicity [9] . The TNM system devised by the AJCC is designed to stratify cancer patients into different stages based on the characteristics of the primary tumor T represents size of cancer, N represents lymph node involvement and metastasis is represented by M. As of recent situation of reporting high number of patients with oral cancer as mentioned above, a study was needed to carry out in Bangladesh. In Bangladesh, as medical facilities centered around Dhaka are involved in treatment of oral cancer, we can utilize our expertise to know the factors and co-factors related to oral cancer which might lead to develop awareness among the people and make treatment policies in local and national level in sequence to international scenario. Material and methods This was descriptive type of cross-sectional study. 162 patients with histopathologicaliy diagnosed oral cancer, from August 2018 to September 2019, attending in outdoor clinic of Department of Oral and Maxillofacial of following 5 tertiary centers in Dhaka: 1. Bangabandhu Sheikh Mujib Medical University (BSMMU) 2. Dhaka Medical College Hospital (DMCH) 3. Sir Sallimullah Medical College and Mitford hospital (SSMC)