Uzer et al. Clin Med Rev Case Rep 2018, 5:209 Volume 5 | Issue 4 DOI: 10.23937/2378-3656/1410209 Citaton: Uzer F, Ozbudak IH, Ozbudak O, Cilli A (2018) Pulmonary Hyalinizing Granuloma in the Dif- ferental Diagnosis of Pulmonary Carcinoma. Clin Med Rev Case Rep 5:209. doi.org/10.23937/2378- 3656/1410209 Accepted: April 03, 2018: Published: April 05, 2018 Copyright: © 2018 Uzer F, et al. This is an open-access artcle distributed under the terms of the Cre- atve Commons Atributon License, which permits unrestricted use, distributon, and reproducton in any medium, provided the original author and source are credited. ISSN: 2378-3656 Open Access Clinical Medical Reviews and Case Reports • Page 1 of 3 • Uzer et al. Clin Med Rev Case Rep 2018, 5:209 Pulmonary Hyalinizing Granuloma in the Diferental Diagnosis of Pulmonary Carcinoma Fath Uzer 1* , I. Hicran Ozbudak 2 , Ömer Ozbudak 3 and Aykut Cilli 3 1 Department of Chest Diseases, Kastamonu State Hospital, Kastamonu, Turkey 2 Department of Pathology, Akdeniz University Faculty of Medicine, Antalya, Turkey 3 Department of Chest Diseases, Akdeniz University Faculty of Medicine, Antalya, Turkey Abstract Pulmonary hyalinizing granuloma (PHG) which should be considered in the differential diagnosis of pulmonary nod- ules of unknown origin is a distinct fbrosing lesion of lung that occurs in middle-aged patients. It has been usually re- ported as case reports in the literature. Patients are usually symptomatic. We present the case which recognized during operation and determined rarely. Keywords Bronchoscopy, Pulmonary hyalinizing granuloma, Lung cancer Case A 62-year-old female presented to the clinic with complaints of dyspnea, cough and sputum. In her his- tory; she had cholecystectomy, hypertension and bio- mass exposure. Family history was unremarkable. On physical examinaton, blood pressure 125/75, pulse 95 and fngertp saturaton was 97%. Other system exam- inatons were normal. Laboratory examinaton revealed *Corresponding author: Fath Üzer, Department of Respiratory Medicine, Kastamonu State Hospital, Kastamonu, Turkey, E-mail: uzerfath@gmail.com CAse RepORt Check for updates Introducton Pulmonary hyalinizing granuloma (PHG) which should be considered in the diferental diagnosis of pulmonary nodules of unknown origin is a distnct fbrosing lesion of lung that occurs in middle-aged patents [1,2]. The ra- diological appearance of the lesion is that of multple, bilateral nodules which sometmes mimic metastatc carcinoma [1-3]. Although the etopathogenesis of PHG is unknown, it has been postulated that it represents an exaggerated immune response, possibly due to chronic granulomatous infectons such as tuberculosis or histo- plasmosis or antgen-antbody complexes so that this immune response may result in depositon of immuno- globulins or immune complexes in the lung [1-8]. A pa- tent with suspected lung cancer was diagnosed pulmo- nary hyalinizing granuloma by transthoracic fne needle aspiraton (TTFNA). We present the case which usually recognized during operaton and determined rarely. Figure 1: Image from chest X-ray.