Moderated Poster Session III 299 Estimation risk for developing recurrent stroke in young adults with ischemic stokes using the Essen Stroke Risk Score: do women and men had differences risk? J Jom Suwanno 1 , JUK Suwanno 2 , K Angkun 3 , K Rajborirug 4 1 School of Nursing, Graduate Nursing Studies, Master of Nursing Science Program in Adult Nursing, Thasala, Nakhon Si Thammarat, Thailand, 2 Stroke Care Unit, Hat Yai Hospital, Division of Nursing, Department of Medicine, Hat Yai, Songkhla, Thailand, 3 Division of Nursing, Nursing Administration, Hat Yai, Songkhla, Thailand, 4 Hat Yai Hospital, Department of Internal Medicine, Neurology, Hat Yai, Songkhla, Thailand Funding Acknowledgements: Topic: Peripheral Vascular and Cerebrovascular Disease - Other Background Prevalence of ischemic stroke in young adults is increasing worldwide. Risk factors of stroke in young women and men are diverse. Women and men may have differences cardiovascular disease (CVD) risk factors, which related to recurrent stroke and major adverse cardiovas- cular events. Determine sex differences in risk for developing recurrent stroke may help us improving secondary prevention protocols. Purpose We examined whether young ischemic stroke women and men had differences risk for devel- oping recurrent stroke. Methods We analyzed data from the five-year stroke registry of a tertiary care, teaching, and referral hospital in the South of Thailand. There were 3,135 ischemic strokes admitted during October 2011 and February 2016, which 583 (18.6%) of young adults aged 16-50 years old. Approximately one-third was women (35.2%). Risk for recurrent stroke was identified based on the Essen Stroke Risk Score (ESRS). ESRS score ranged from 0 to 9, the higher the score indicated the higher risk for recurrent stroke. Two risk levels were identified as low (score 0-2), and high (score 3-9). Mann-Whitney U test, Chi-square, and univariate estimates of odds ratio (95%CI) were calculated to compare sex differences. Results Most common CVD risks in women were hypertension (49.8%), and diabetes (22.0%), whereas smoking (83.6%), alcohol drinking (78.6%), and hypertension (41.0%) were more common in men. Compared to men, women had lower total score on ESRS (U=7.58, p=0.000). They had higher score on the index of hypertension (U=2.03, p=0.042), but less score on smoking (U=17.11, p=0.000). There were a less number of women than did men in the high risk level for recurrent (2.4 vs 16.7%; Chi = 26.11; OR 0.19[95%CI 0.08- 0.44]). An increment odds ratio of hypertension (OR 1.25, 95%CI 1.01-1.56), and previous myocardial infarction (OR 3.12, 95%CI 2.59-3.75) were found in women compared to men. In contrast, men had increment odds ratio of smoking (OR 3.72, 95%CI 2.99-4.63), and alcohol drinking (OR 3.12, 95%CI 2.59-3.75). Conclusions Young stroke women and men had differences risks levels and risk factors for developing recurrent stroke. Although women had fewer score and lower level for recurrent, they had higher risk in hypertension and myocardial infarction. Higher risk in men was mainly attrib- uted by smoking. Hence, secondary prevention to reduce recurrent event should be consider- ing to these sex differences. 301 A quality improvement project to facilitate annual cardiovascular disease risk assessment in Rheumatoid Arthritis patients: A Mid-Western experience MU Khan 1 , UA Khan 2 , F Adeeb 1 , S Alwin 1 , E Maher 3 , J Devlin 1 , A Fraser 1 1 University Hospital Limerick, University of Limerick, Rheumatology, Limerick, Ireland, 2 University hospital Limerick, University of Limerick, Cardiology, Limerick, Ireland, 3 University of Limerick, limerick, Ireland Funding Acknowledgements: Topic: Cardiovascular Disease in Special Populations - Other Background: Rheumatoid arthritis (RA) is associated with accelerated atherosclerosis and increased risk of morbidity and mortality from cardiovascular disease (CVD) as compared to age and gender-matched controls due to the high prevalence of traditional CVD risk factors (tCVD-RF) and systemic inflammation. EULAR(European League Against Rheumatism) recommends annual cardiovascular risk assessment (CRA) for patients with RA. The 2016 ESC guidelines on CVD prevention in clinical practice recommended a systematic CVD assessment as a screening tool in targeted high-risk subpopulation such as RA, using the SCORE system that gives an estimate of the 10-year risk of a first fatal atherosclerotic event. Objective: Three-fold re-audit aims: 1.to determine the prevalence of the tCVD-RF (diabetes, hypertension, hyperlipidemia, long term corticosteroid use and smoking) in RA patients 2.to assess management of CVD risk in RA patients in comparison to the EULAR recom- mendations and ESC guidelines 3.to identify RA disease activity control Method: This study involved 2-teaching hospitals in Mid-West region of Ireland. 100 RA patients were recruited between May-June 2016 and January-February 2017 in each audit and reaudit phases respectively. Demographic data, disease duration and activity, Rheumatoid Factor/ACPA status, concomitant ESR and CRP, DAS28, tCVD-RFs, past history of ischemic heart disease (IHD), related co-morbidities (TIA, CVA, PVD, aortic aneurysm) and drug history (current RA, anti-hypertensive and lipid lowering medications) was noted.Data on blood pressure (BP), lipid profile and blood glucose (random, fasting or HbA1c) were sought in the preceding 4-years, and if treatment were commenced as per the guidelines. The 10-year risk of fatal CVD was calculated using the Systematic COronary Risk Evaluation (SCORE) chart: total cholesterol/HDL ratio was used as measure of lipid profile and risk was multiplied by 1.5 if patient had 2 of these 3 criteria: disease duration of >10 years, positive RF/ACPA, presence of severe extra-articular manifestations. Result: Overall results are summarized in Figure. There was improvement in the efficiency of Abstract No: 301. S58 EuroPRevent Congress Abstracts May 2018