Introduction South Asian countries, a home of over one billion people, have been struggling to prevent the spread of the coronavirus disease 2019 (COVID-19) pandemic. As of 14 September 2020, more than 5 million people have been infected with over 90,000 deaths in last six months. Despite various public health efforts, epidemiologic growth curve has not yet been flattened in most south Asian countries except Pakistan 1 . Severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) infection predominantly results in an acute respiratory illness including a myriad of extrapulmonary symptoms. The clinical spectrum ranges from asymptomatic or mildly symptomatic flu-like illness to potentially life-threatening critical conditions 2 . Studies have shown that the clinical spectrum of COVID-19 can vary among different ethnicities and geographical locations across the world 3 . There is not much information on the clinical manifestations of COVID-19 in South Asian context. Documentation of clinical profile from various geographic locations is essential for future scientific studies and clinical management. South countries including Bangladesh are similar in terms of socio-demographic and lifestyle related factors and therefore clinical symptoms are expected to be similar as well. Owing to a population of over 160 million, inadequate healthcare system, and poor personal hygiene among the general population, Bangladesh is considered one of the high-risk countries for coronavirus spread. The first official case of COVID-19 was reported on 8 March 2020, and the epidemic still appears to be in a growing phase. As of 14 September 2020, a total of 339,332 cases and 4,759 deaths have been reported from Bangladesh 1 . However, the information on clinical manifestations from Bangladesh is scarce in the literature. Therefore, this study is aimed to document the clinical spectrum of COVID-19 patients attending fever clinics in Bangladesh. Materials and Methods This was a cross-sectional study conducted among real-time polymerase chain reaction (RT-PCR) confirmed COVID-19 patients attending the fever clinic of a dedicated COVID-19 hospital (Kurmitola general hospital) in Dhaka city of Bangladesh and two Upazila health complexes from different districts (Jessore and Jhenaidah) from 5 July to 18 July 2020. Diagnosis of SARS- COV-2 infection and assessment of severity were done based on the WHO interim guidance. Clinical features including respiratory rate, oxygen saturation and chest imaging were used to categorize the severity of the disease. Mild, moderate and severe diseases were considered as non-critical disease. The mild disease was defined by any RT-PCR positive patient of COVID-19 without radiological features of pneumonia or hypoxia (SpO 2 e90% on room air). Moderate disease (pneumonia) was defined by clinical signs (fever, cough, dyspnea, fast breathing) and radiological features of pneumonia but no signs of severe pneumonia, including SpO 2 ≥90% on room air in adolescents and adults. Clinical Characteristics of Noncritical Patients with Coronavirus Disease 2019 (COVID-19): Lessons from Bangladesh Md. Shahed Morshed 1  2 ; Abdullah Al Mosabbir 2 , Prodipta Chowdhury 3 , Sheikh M Ashadullah 4 and Mohammad Sorowar Hossain 2 1 Emergency medical officer, Kurmitola general hospital, Dhaka, Bangladesh, 2 Department of Emerging and Neglected Diseases, Biomedical Research Foundation, Dhaka, Bangladesh, 3 Emergency medical officer, Keshabpurupazilla health complex, Jessore, Bangladesh, 4 Medical officer, Shailkupaupazilla health complex, Jhenaidah, Bangladesh The scientific literatures on clinical manifestations of coronavirus disease 2019 (COVID-19) patients from South Asian countries including Bangladesh are limited. Documentation of clinical spectrum from various geographic locations is vital for future scientific studies and clinical management. This study is aimed to report the sociodemographic and clinical characteristics of noncritical patients with COVID-19 in Bangladesh. We conducted a cross-sectional study at three dedicated COVID-19 hospitals of Bangladesh. The severity of the COVID-19 cases was assessed based on the WHO interim guidance. Data were collected only from non-critical COVID-19 patients as critical patients required immediate management. A total of 103 real-time polymerase chain reaction (RT-PCR) confirmed noncritical COVID- 19 patients were included. Most of the patients (71.8%) were male. Mild, moderate and severe illness were assessed in 74.76%, 9.71% and 15.53% of patients respectively. Nearly 52.4% patients had a co-morbidity, with hypertension being the most common (34%), followed by diabetes mellitus (21.4%) and ischemic heart disease (9.7%). Fever (78.6%), weakness (68%) and cough (44.7%) were the most common clinical manifestations. Other common symptoms included loss of appetite (37.9%), difficulty in breathing (37.9%), loss of taste or smell (35.0%), headache (32%) and body ache (32%). The median time from onset of the first symptom to attending hospitals was 7 days (interquartile range: 4 - 10). This study will help both the clinicians and epidemiologists to understand the magnitude and clinical spectrum of COVID-19 patients in South Asian perspective including Bangladesh. Key words: COVID-19, clinical characteristics, pandemic, Bangladesh, South Asia Original Article Bangladesh J Microbiol, Volume 37, Number 2, December 2020, pp 42-46 Correspondence to: Mohammad Sorowar Hossain, PhD, Department of Emerging and Neglected Diseases, Biomedical Research Foundation, Dhaka, Bangladesh. Contact number: +88 01963378441, mail: sorowar.hossain@brfbd.org