Maryam Hani Abduljalal Propolis: biochemical and .. 216 Ann Coll Med Mosul December 2021 Vol. 43 No.2 Propolis: biochemical and clinical evaluation Maryam Hani Abduljalal* , Omar Mohammed Yaya* , Maher Abdul Satar Ibrahim* , Imad A Thanoon** *Department of Biochemistry , College of Medicine , University of Mosul , **Department of Pharmacology , College of Medicine , University of Mosul , Mosul , Iraq Correspondence: omermohammed@uomosul.edu.iq (Ann Coll Med Mosul 2021; 43 (2):216-219). Received: 7 th Dece. 2021; Accepted: 22 th Dece. 2021. ABSTRACT Propolis is a glue-like substance which produced by honey bees, it is related to honey. It is also called bee glue as they use it to reconstruct their hives and for the hives maintenance. They make propolis by mixing many substances like bee wax, saliva, exudate collected from trees, sap flows and other sources. Many studies have made concerning importance of propolis and it is wide medical benefits as it is role in improving immunity, reducing elevated blood pressure, curing many allergic conditions and dermatological diseases. The aim of this review is to enumerate some of its chemical constitutions and it is role in treating some medical conditions. Keywords : propolis, bee glue, honey and bees . تق يي م سر ي ر ي و ب ا ي و كي م ي ائ ي ل عكبرنحل ال يش ي ىا ي عثذل انجل* ، ش عذ يح ي ح ي * ، ش يا عثذراس انس اتشا ي ى* ، اد ع عثذنجثاس ا ر** * فشعياء انكيياذيح انح، كهيح ا ن طة، جايعحصم ان، ** فشع عهىيح الد، كهيح ا ن طة، جايعح صم ان، صم ان، انعشاق خلصة ال سرخذيث يم حيح غشاء ان اً أيعيس .دج انعسماذرعهك ت حم انعسم ارج ي)غانص(نغشاءح تاادج شثيس ينيت انثش ضج انعذيذك ي غشي عنيس ذکتعح انثشانخليا. ص از حنصيا حم اناء خليا لعادج تنهعاب انعسم, اعاد يثم ش ان ي يصادس أخش ساخنعصاتعط ا لشجاس اا يعالفشاصاخ انری يرى ج . خفط اعح ان ا فی ذحسيً س حيث ذهعة داسعح ائذ غثيحا فن نيستيح انثشند أاخ انری ذسا انذساذ يک انعذيا اسيح أيشاض انحسذ يلج انعذيع شذفع ظغػ انذو انشاض انجهذيحالي . اللمفتاحيةت ا كلما: انعكثش،  ص غحم ان، انعسم حم ان. INTRODUCTION oney bees made many beneficial materials in their hives starting from honey, bee wax, bee bread and propolis that have a clear role in curing many diseases. Honey is a complex substance that made of nectar, stored in the honey comb. Bee wax, used to build the walls of the comb. Like honey, beeswax has many uses such as candle manufacturing, soap, cosmetic products and many pharmaceutical benefits. Bee bread are made by Worker bees, they make bee bread by mixing pollen, glandular secretions and honey, after a fermentation to be allowed, bee bread is prepared. This fermentation process will release from the pollens, additional nutrients containing antibiotics and fatty acids so it has many medical uses too. 1,2 Propolis Is a resinous substance collected by honeybees from different sources to seal the unwanted opening in their hives. Despite propolis may cause allergic reaction for many peoples, it have a lot of medical implementation like cold syrups and flu remedies 3-5 . H