Orthodontic Journal of Nepal, Vol. 9 No. 2, July-December 2019 52 INTRODUCTION The issue of optimal timing in dentofacial orthopedicsis intimately related to identifcation of periods of acceleratedgrowth that contribute signifcantly in correction of skeletal imbalances in individual patient. Several clinical studies have shown that the greatest response to functional jaw orthopedics tends to occur during circumpubertal growth period. 1 Before maximal pubertal growth the skeletal response were less in subjects as well as after maximal pubertal growth. 2,3 Therefore, to assess growth spurts for the determination of the optimal growth modifcation treatment timing Dr Natasha Patil, 1 Dr Neha Maheshwari, 2 Dr Rohit Sharma, 3 Dr Shashank Soni, 4 Dr Ashish Kushwah 5 1 Senior Lecturer, Department of Orthodontics, M.P.C.D & R.C. Gwalior, 2 Private practitioner, Nanda Dental Care, 3 Senior Lecturer, Department of Prosthodontics, 4 Post Graduate Student, Department of Orthodontics, M.P.C.D & R.C. Gwalior, 5 Post Graduate Student, Department of Orthodontics, Teerthankar Mahaveer University, India Correspondence: Dr. Kushwah Ashish; Email: ashishkushwah998@gmail.com Correlation between Chronological Age, Cervical Vertebral Maturation and Fishman’s Skeletal Maturity Indicators in Central India Population ABSTRACT Introduction: Skeletal maturity indicators are very important indicators when diagnosing and panning the treatment in growing population. Cervical Vertebrae Method( CVM) and Fishman’s Skeletal Maturity Indicators are two commonly used methods for the diagnosis and treatment planning. The aim of the study was to investigate the correlation between cervical vertebral maturation (CVM)and Fishman’shand-wrist skeletal maturity indicator and chronological age by including subjects within the range of circumpubertal growth spurt in Central India. Materials & Method: One Twenty Five contemporary hand-wrist and lateral cephalometric radiographs from population of Central India were randomly selected and analyzed. All subjects were within the circumpubertal period i.e. female subjects were between 10 and 15 years of age, and the male subjects were between 12 and 17 years of age. The hand-wrist bone analysis was evaluated using the method developed by Fishman whereas cervical vertebra bone analysis was evaluated using the method developed by Baccetti and coworkers. These two methods and chronological age were correlated using the Spearman rank correlation analysis. Result: CVM was signifcantly correlated with hand-wrist maturation (r=0.8868).However low correlation was found between the CVM and chronological age( r =0.7139) and little correlation was found between the HWM and chronological age ( r =0.6892). Conclusion: CVM is a valid indicator of skeletal growth during the circumpubertal growth period and has a high correlation with the HWM for the Central India population. Howeverchronological ageis not suitable to measure skeletal maturity as shown by the low correlations found between the chronological age and both CVM and HWM. Keywords: Cervical vertebra maturation, Chronological age, Hand-wrist maturation, Skeletal maturity. Research Article a biologic indicators series were used.These methods includes characteristics of sexual maturation, facial growth and peak height velocities, chronological age, dental development, body weight,body height and handwrist maturity. 4 Successful growth modifcation in orthodontics is dependent on skeletal maturation.5 Hand wrist maturation (HWM) analysis is the most widly used and a classical method for evaluation of skeletal age. HWM is the highly reliable method done by radiograph. However, an addition exposure of ionizing radiation of the orthodontic patient required to the routine radiographic records for this analysis. 6