World Journal of Neuroscience, 2018, 8, 350-362 http://www.scirp.org/journal/wjns ISSN Online: 2162-2019 ISSN Print: 2162-2000 DOI: 10.4236/wjns.2018.83028 Aug. 1, 2018 350 World Journal of Neuroscience Emotion Evaluation of Four Generations of Woman from a 104-Year Old Ancestress Gilles Sicard 1 , Guy Escoffier 1 , Elodie Salebert 1 , Abdessadek El Ahmadi 2 , Sadelli Kevin 1 , François S. Roman 1* 1 INP Institut de Neurophysiopathologie, Faculté de Médecine de Marseille, Aix-Marseille Université, Marseille, France 2 Laboratoire de Neurosciences Sensorielles et Cognitives, Aix-Marseille Université, Marseille, France Abstract Normal aging is associated with declines of perception and cognition. In- versely, emotions seem to be preserved compared to younger adults. Viewing, neutral, dramatic and comic films, emotions were evaluated in four genera- tions of woman from a 104-year old ancestress. At the very old age, from this case report, emotions were differently expressed while arousal was still pre- served. A constant emotion of scare was expressed during the viewing of these three films (p < 0.001) with significant higher level of disgust (p ≤ 0.01). Only perceptual deficiency cannot explain this difference as cognitive tasks revealed a mild cognitive impairment detected by the Mini Mental State Ex- amination and a substantial impairment on the executive functions by using the Delayed response tasks. These results emphasize that some emotions in a normal aging centenarian are still present, even if not appropriates, and dif- ferent in comparison to a young adult control group. From this study, it is expected that emotion analysis in old adults viewing selected short films will predict longevity and could discriminate normal processes occurring during normal aging from neurodegenerative diseases. Keywords Emotion, Very Old Aging, Facial Analyses, 104-Year Old Case Report 1. Introduction Although, normal age-related changes in cognition are not uniform across all cognitive domains or across all individuals, it is well known that basic cognitive functions most affected by age are attention and memory [1]. Perception also shows significant age-related declines attributable mainly to decline of sensory How to cite this paper: Sicard, G., Escof- fier, G., Salebert, E., El Ahmadi, A., Kevin, S. and Roman, F.S. (2018) Emotion Evalua- tion of Four Generations of Woman from a 104-Year Old Ancestress. World Journal of Neuroscience, 8, 350-362. https://doi.org/10.4236/wjns.2018.83028 Received: April 3, 2018 Accepted: July 29, 2018 Published: August 1, 2018 Copyright © 2018 by authors and Scientific Research Publishing Inc. This work is licensed under the Creative Commons Attribution International License (CC BY 4.0). http://creativecommons.org/licenses/by/4.0/ Open Access