The Difference between IQOS and Continued Smoking Response to the article entitled “PMI’s own in vivo clinical data on biomarkers of potential harm in Americans show that IQOS is not detectably different from conventional cigarettes,” by Stanton Glantz, 2018 1 Gizelle Baker, Christelle Haziza, Matthew Hankins, Nicola Lama, Serge Maeder, Patrick Picavet, Maurice Smith, Patrick Vanscheeuwijck, and Manuel C. Peitsch 2 Philip Morris International R&D 1 Department of Medicine/Division of Cardiology, University of California San Francisco, San Francisco, CA, USA; Center for Tobacco Control Research and Education, University of California San Francisco, San Francisco, CA, USA 2 PMI Research and Development, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland. Authors are listed in alphabetical order.