374 OPEN ACCESS http://scidoc.org/IJOES.php Alzahrani M, Rehman MA, Bahttab S. Vision Loss Case of Bardet Biedl Syndrome. Int J Ophthalmol Eye Res. 2018;6(3):374-376. International Journal of Ophthalmology & Eye Science (IJOES) ISSN 2332-290X Vision Loss Case of Bardet Biedl Syndrome Case Report Alzahrani M 1* , Rehman MA 2 , Bahttab S 3 1 Resident, Department of Ophthalmology, East Jeddah Hospital, Jeddah, Saudi Arabia. 2 Senior Specialist, Department of Ophthalmology, East Jeddah Hospital, Jeddah, Saudi Arabia. 3 Ophthalmology consultant, Department of Ophthalmology, East Jeddah Hospital, Jeddah, Saudi Arabia. Introduction Bardet Biedl Syndrome is a rare hereditary autosomal recessive disorder with multisystem involvement. The prevalence 1:140,000 and 1:160,000 [1, 2]. While the number prevalence increased with consanguinity marriage by 1:65,000 [3]. The complete BBS rep- resented by obesity, retinal rods and cons degeneration, mental retardation, postaxial polydactyly, stunted growth, renal involve- ment and hypogonadism [4]. The review would give the funda- mental familiarity with the syndrome manifestation that will have an effect in early control of disease and directing advantages to the patients and their families. Hence, we conducted this study along with clinical profle of Bardet Biedl Syndrome patient. Case Report A women of forty-three years, known case of retinitis pigmentosa and presented to East Jeddah Hospital, Ophthalmology depart- ment requesting a medical report, by history, she was not able to see at night for years then both day and night lost with noticed horizontal nystagmus. Patient has past history learning diffculties. The rest of systemic review is unremarkable. By examination: pa- tient underwent for dysmorphology examination, anthropometric measurements, ophthalmology evaluation such microscopic ex- amination, fundus camera and Optical Coherence Tomography (OCT). Patient was conscious, mild cognitive impairment and no cerebellar signs, including coordination and gait instability. Exam- inations of power, tone grades and Sensation of all limbs were intact. Her BMI is 30.8 obese, other fndings were polydactyly of lower limbs, Figure 1 upper limb polydactyly has had excised at child- hood. The rest of examination was irrelevant. Laboratory and ra- diology have obtained, include of complete blood count, random blood sugar, HgA1c, liver, renal function tests, and abdominal/ pelvic ultrasonography, Electrocardiography (ECG) that were found to be normal. Ocular History Visual Acuity: light perception both eyes and horizontal nystag- mus in both eyes. Slit Lamp: Lids/Lashes, Conjunctiva and Cornea are Normal. Goldman Tonometry: OD: 16 mmHg OS: 14 mmHg at 2:30 PM. Fundus Exam: multiple bony spicules and attenuated vessels with pale optic disc. Retinitis pigmentosa on fundoscopy Figure 2 thinned and atrophy of RBE Figure 3. Abstract We would like to report a rare case of Bardet Biedl Syndrome of a women forty-three years, known case of Retinitis pig- mentosa presented for medical report, after ocular and systemic assessment we found she is obese, moon face, and has extra toes of both feet and some other fnding which was diagnosed later on Bardet Biedl Syndrome. We documented this rare case for its important in clinical practice for regular systemic follow up and therefore, subsequently requiring management accordingly. Keywords: Bardet Biedl; Retinitis Pigmentosa; Obesity; Polydactyly. *Corresponding Author: Mazen Alzahrani, Resident, Department of Ophthalmology, East Jeddah Hospital, Jeddah, Saudi Arabia. E-mail: D.mazen@hotmail.com Received: January 22, 2018 Accepted: February 28, 2018 Published: March 01, 2018 Citation: Alzahrani M, Rehman MA, Bahttab S. Vision Loss Case of Bardet Biedl Syndrome. Int J Ophthalmol Eye Res. 2018;6(3):374-376. doi: http://dx.doi.org/10.19070/2332-290X-1800075 Copyright: Alzahrani M © 2018. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.