Research Article
Analysis of Blood Transfusion Data Using Bivariate
Zero-Inflated Poisson Model: A Bayesian Approach
Tayeb Mohammadi,
1
Soleiman Kheiri,
2
and Morteza Sedehi
3
1
Student’s Research Committee, Shahrekord University of Medical Sciences, Shahrekord, Iran
2
Social Health Determinants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
3
Epidemiology and Biostatistics Department, Shahrekord University of Medical Sciences, Shahrekord, Iran
Correspondence should be addressed to Soleiman Kheiri; kheiri@skums.ac.ir
Received 14 April 2016; Accepted 16 August 2016
Academic Editor: Dong Song
Copyright © 2016 Tayeb Mohammadi et al. Tis is an open access article distributed under the Creative Commons Attribution
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly
cited.
Recognizing the factors afecting the number of blood donation and blood deferral has a major impact on blood transfusion. Tere
is a positive correlation between the variables “number of blood donation” and “number of blood deferral”: as the number of return
for donation increases, so does the number of blood deferral. On the other hand, due to the fact that many donors never return to
donate, there is an extra zero frequency for both of the above-mentioned variables. In this study, in order to apply the correlation
and to explain the frequency of the excessive zero, the bivariate zero-infated Poisson regression model was used for joint modeling
of the number of blood donation and number of blood deferral. Te data was analyzed using the Bayesian approach applying
noninformative priors at the presence and absence of covariates. Estimating the parameters of the model, that is, correlation, zero-
infation parameter, and regression coefcients, was done through MCMC simulation. Eventually double-Poisson model, bivariate
Poisson model, and bivariate zero-infated Poisson model were ftted on the data and were compared using the deviance information
criteria (DIC). Te results showed that the bivariate zero-infated Poisson regression model ftted the data better than the other
models.
1. Introduction
Blood transfusion is so important in health system that it
plays a big part in saving many people’s lives in normal and
emergency situations. Furthermore, it has a noticeable impact
on improving the quality of life and consequently the life
expectancy of chronic patients. Nevertheless, many patients
either die due to lack of access to safe blood transfusion
or at least sufer from it. According to the World Health
Organization report, about one percent of the population of
every country is in need of blood donation [1]. Today, the
need for blood and its products is increasing day by day [2].
Since some diseases may be caused by blood transfusion,
screening the donors and detecting potential healthy donors
are of great importance [3]. For that matter, lack of healthy
donors has always been a serious problem for blood banks to
supply sufcient and healthful blood [4, 5]. Terefore, one of
the main goals of blood transfusion centers is detecting and
preserving healthy donors and preventing unhealthful blood
donation which may cause many diseases to be created or
aggravated [2]. Nonetheless, even from among those who are
eligible to donate blood only a small portion really become
blood donors [6]. Inasmuch as the screening test is done at
each donation to separate healthful from unhealthful blood,
the more the blood donation is, the higher the chances of
getting healthful blood will be. Tat is why recognizing the
factors which infuence blood donation is of great importance
in attracting potential donors and turning them into regular
donors [3]. From among all the laboratory screening methods
to prevent the transference of infection through blood, the
only truly efective method is to select healthy donors and not
allow ineligible donors to donate blood [7]. People who are
not eligible to donate blood are called “deferred donors” [8].
Most deferrals are “temporary” and exist due to taking certain
medications before donation, high or low blood pressure,
anemia, high-risk behavior, and so forth. Tese deferrals
Hindawi Publishing Corporation
Computational and Mathematical Methods in Medicine
Volume 2016, Article ID 7878325, 7 pages
http://dx.doi.org/10.1155/2016/7878325