376 Copyright © 2019, IGI Global. Copying or distributing in print or electronic forms without written permission of IGI Global is prohibited. Chapter 16 DOI: 10.4018/978-1-5225-8365-3.ch016 ABSTRACT This article describes how a healthcare delivery drone has the potential for developing countries to leapfrog the development of traditional transportation infrastructure. Inaccessible roads no longer will prevent urgent delivery of blood, medications or other healthcare items. This article reviews the current status of innovative drone delivery with a particular emphasis on healthcare. The leading companies in this feld and their diferent strategies are studied. Further, this article reviews the latest decision models that facilitate management decision making for operating a drone feet. The contribution in this article of two new models associated with the design of a drone healthcare delivery networks will facilitate a more timely, efcient, and economical drone healthcare delivery service to potentially save lives. INTRODUCTION There is a major new technology that is destined to be a disruptive force in the field of transportation: the drone. Just as the mobile phone allowed developing countries to leapfrog older technologies for personal communication, the drone has the potential to leapfrog traditional transportation infrastructure. Drones are not dependent on a well-developed road infrastructure because they fly to their destination. Drones are commonly known as unmanned aerial vehicles (UAVs) (Choi-Fitzpatrick et al., 2016). Alternative terms include Unmanned Aircraft (UA), Remotely Operated Aircraft (ROA), Remotely Piloted Vehicle (RPV) and Remotely Piloted Aircraft (RPA) (Clarke, 2014). Models for Drone Delivery of Medications and Other Healthcare Items Judy E. Scott University of Colorado, USA Carlton H. Scott University of California, USA