COMMENTARY
46th ESCP symposium on clinical pharmacy “Science meets
practice: towards evidence-based clinical pharmacy services”,
Heidelberg, Germany, October 9th–11th, 2017
Published online: 8 December 2017
© Springer International Publishing AG, part of Springer Nature 2017
Oral communications I: Community pharmacy
CP-PC001: Clinical decision support and creatinine point of care
testing for antibiotics
Mette Heringa
*,1,2,3
, Annemieke Floor-Schreudering
1,2
, Peter A.G.M.
De Smet
4
, Marcel L. Bouvy
1,2
1
SIR Institute for Pharmacy Practice and Policy, Leiden,
2
Division of
Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute
for Pharmaceutical Sciences, Utrecht University, Utrecht,
3
Health
Base Foundation, Houten,
4
Departments of Clinical Pharmacy and IQ
Healthcare, University Medical Centre St Radboud, Nijmegen,
Netherlands
Background and Objective: An impaired renal function, which is
common in the elderly, is an important risk factor for medication
related hospital admissions. We aimed to investigate the management
of drug therapy alerts on safe use of antibiotics in elderly patients with
(potential) renal impairment in combination with the option of crea-
tinine point of care testing (PoCT) in community pharmacy practice.
Setting and Method: Community pharmacists used a clinical deci-
sion support system (CDSS) for seven antibiotics. Alerts were
generated during prescription processing in case of previously reg-
istered renal impairment, and when no information on renal function
was available for patients aged 70 and over. Pharmacists could per-
form PoCT when renal function could not be retrieved from other
health care providers. Actions were registered in the CDSS. A ret-
rospective descriptive analysis of alert management and medication
dispensing histories was performed. Logistic regression was per-
formed on PoCT cases to analyse determinants of identifying patients
with renal impairment.
Main outcome measures: Nature and frequency of CDSS alerts,
interventions, and performed PoCT; determinants for identifying
patients with impaired renal function by PoCT in community
pharmacy.
Results: 351 pharmacists registered the management of 88,391 alerts
for 64,763 patients. For 49,178 patients (75.9%) renal function was
registered in the CDSS. 1.8% of the alerts (n = 1532) led to dose
adjustment or drug replacement. Pharmacists performed 1988 PoCTs
(2.2%). In 9.2% of these PoCTs, the renal function was impaired
(estimated glomerular filtration rate ≤ 50 ml/min/1.73 m
2
).
Determinants for finding renal impairment were higher age and higher
number of medicines in use.
Conclusion: Implementation of a CDSS and possibility to perform
PoCT in community pharmacies prevented potential inappropriate
(dosing of) antibiotics in elderly patients with renal impairment.
Pharmacists retrieved renal functions mostly from other health care
providers. Creatinine PoCT was of added value in a limited number of
cases, especially in the very elderly.
CP-PC002: Novel technology-enabled pharmacist and patient
education program enhances adherence to stroke prevention
medications
John Papastergiou
*,1
, Akeel Jaffer
2
, Kori Leblanc
3
, Bill Semchuk
4
,
Stuart Menzies
5
1
Assistant Professor, University of Toronto,
2
Pharmacist/Owner,
Shopper’s Drug Mart,
3
Pharmacy, University of Toronto, Toronto,
4
Clinical Pharmacy Services Regina Qu’Appelle Health Region,
University of Saskatchewan, Regina,
5
CTC Communications,
Mississauga, Canada
Background and Objective: Atrial fibrillation (AF), the most com-
mon heart rhythm disturbance in Canadians, increases the risk of fatal
and permanently disabling stroke. Antithrombotic treatment decreases
this risk by up to 65%. The Canadian Cardiovascular Society (CCS)
AF guidelines indicate that Non-vitamin K oral anticoagulants
(NOACs) are the preferred agents for stroke prevention in eligible
patients. Optimizing the protection conferred by these agents requires
both high adherence and persistence. Registries and claims database
evaluations indicate that persistence rates with NOACs range from
60% to over 90%; decreases in persistence have been associated with
increased stroke and death.
Setting and Method: Pharmacists were invited to participate in a
web-based education program, PAACT-AF, with the goal of helping
counsel and educate patients with AF taking NOACS. Pharmacists
were asked to assess up to 20 patients each, and for each patient a
structured questionnaire measured knowledge and adherence. The
platform outputted a counselling checklist based on the individual
patient being assessed. Patients were followed for 1-4 months and a
subsequent questionnaire was completed.
123
Int J Clin Pharm (2018) 40:203–317
https://doi.org/10.1007/s11096-017-0565-9