443 Julián Fernández Navajas University of Zaragoza, Spain Antonio Valdovinos Bardají University of Zaragoza, Spain Robert S. H. Istepanian Kingston University, UK José García Moros University of Zaragoza, Spain José Ruiz Mas University of Zaragoza, Spain Eduardo Antonio Viruete Navarro University of Zaragoza, Spain Carolina Hernández Ramos University of Zaragoza, Spain Álvaro Alesanco Iglesias University of Zaragoza, Spain Chapter 2.8 Design of an Enhanced 3G-Based Mobile Healthcare System Copyright © 2009, IGI Global, distributing in print or electronic forms without written permission of IGI Global is prohibited. AbstrAct An enhanced mobile healthcare multi-collab- orative system operating over Third Generation (3G) mobile networks is presented. This chapter describes the design and use of this system in different medical and critical emergency sce- narios provided with universal mobile telecom- munications system (UMTS) accesses. In these environments, it is designed to communicate healthcare personnel with medical specialists in a remote hospital. The system architecture is based on advanced signalling protocols that al- low multimedia multi-collaborative conferences in IPv4/IPv6 3G scenarios. The system offers real-time transmission of medical data and vid- eoconference, together with other non real-time services. It has been optimized specifcally to operate over 3G mobile networks using the most appropriate codecs. Evaluation results show a reliable performance over IPv4 UMTS accesses (64 Kbps in the uplink). In the future, advances in m-Health systems will make easier for mobile patients to interactively get the medical attention and advice they need. INtrODUctION Mobile health (m-health) is an emerging area of telemedicine in which the recent development in mobile networks and telemedicine applications