Pharmacologyonline 2: 97-101 (2010) Newsletter Ahanjan et al. 97 ANTIBACTERIAL PROPERTY OF FRUITS OF PARROTIA PERSICA AGAINST SOME HUMAN PATHOGEN Mohammad Ahanjan 1 *, Raveesha, K. A. 2 , M. Azadbakht 1 and M. Nasorallahie 1 1 Microbiology and immunology department, Mazandaran University of Medical Sciences, Sari, Iran, 2 Department of Studies in Botany and Microbiology, University of Mysore, Manasagangotri, Mysore 570 006, India. *Corresponding author:. E-mail: ahanjan2007@gmail.com. Tel: +981513543081-3 Summary Ethanol and methanol, extracts of fruits of Parrotia persica were evaluated for antibacterial activity. The zone of inhibition varied from 4.5 to 19.5 mm. The highest inhibition was obtained with methanol. The minimal inhibitory concentration (MIC) value of the methanol extract for the test bacteria ranged between 3.12 and 6.25 mg/ml. The results scientifically validate the use of this plant in the traditional medicine of Iran. Key words: Parrotia persica, antibacterial activity, traditional medicine. Introduction Parrotia persica(family Hamamelidaceae) is an important plant used the treatment of bone fracture and for treatment of some infections in the traditional medicine of Iran (1&2). Hence, solvent extracts of fruits of P. persica were quantitatively screened for antibacterial activity against five important human pathogenic bacteria, Hot extraction is more efficient, where the plant material is boiled in a solvent for a stipulated period. Soxhlet extractor is the ideal choice for hot extraction where with minimum solvent complete extraction is effected (3). Concentrating the extracts need careful consideration. Since nearly all of the identified compounds from plants which are active against microorganisms are aromatic or saturate organic compounds, they are most often obtained through initial ethanol or methanol extraction. Materials and Methods The fruit is a two-parted capsule (Fig. 1) containing two seeds; one in each half.