Kalam et al Journal of Drug Delivery & Therapeutics. 2020; 10(4):234-237 ISSN: 2250-1177 [234] CODEN (USA): JDDTAO Available online on 15.07.2020 at http://jddtonline.info Journal of Drug Delivery and Therapeutics Open Access to Pharmaceutical and Medical Research © 2011-20, publisher and licensee JDDT, This is an Open Access article which permits unrestricted non-commercial use, provided the original work is properly cited Open Access Review Article Taryaq-i-Waba‘i: A review on Potent Compound Formulation of Unani Medicine with special reference to epidemic/pandemic diseases Mohd Afsahul Kalam * 1 , Abdul Haseeb 2 , Mohd Sheeraz Mushtaq 3 , Zaffar Hussain 4 *1. Scientist Level-1, Regional Research Institute of Unani Medicine, Srinagar, India 2. PG Scholar, Department of Ilmul Advia, Regional Research Institute of Unani Medicine, Srinagar, India 3. Scientist Level-1, Regional Research Institute of Unani Medicine, Srinagar, India 4. Professor, Department of Moalajat, Regional Research Institute of Unani Medicine, Srinagar, India ABSTRACT Unani System of medicine is one among the oldest systems practiced all over the world. Hippocrates, father of medicine also known as father of epidemiology was the first who had written about the diseases which spread as epidemic or pandemic. After him Galen had mentioned the prevention and management of pandemic/epidemic diseases, and given several drugs for its management. A large number of Unani crude drug and compound formulations have been mentioned in the context of the prevention and management of Waba’i Amrad. Mostly all the Waba’i Amrad have pyrexia with other symptoms according to the involvement of systemic organs. One of the most important formulation is Taryaq-i- Waba‘i, a poly herbal pharmaceutical preparation, in the form of Pills ( Huboob), and is cited by almost all the physicians of Unani Medicine viz; Jalinus, Azam Khan, Ajmal Khan, Kabiruddin etc. in their treatises. In Unani system of medicine, Amrad-i-Waba‘i is described under a broad term which encompasses various contagious diseases which occurs due to impairment of environmental conditions related to air, and water. This compound formulation contains four ingredients, includes Aloe, Myrrh, Crocus and rose water. It is indicated as antidote, anti-epidemic and used for the treatment of epidemic fever, poisonous bites etc. There is no any scientific study has been done on the formulation but it is used by Unani practitioners since time immemorial. So here a brief description of the compound and its ingredients on the scientific basis is being presented for further study on the basis of Amrad-i-Waba‘i. Keywords: Taryaq-i-Waba‘i, Epidemic/Pandemic, Crocus sativus, Unani Medicine. Article Info: Received 24 April 2020; Review Completed 16 June 2020; Accepted 27 June 2020; Available online 15 July 2020 Cite this article as: Kalam MA, Haseeb A, Mushtaq MS, Hussain Z, Taryaq-i-Waba‘i: A review on Potent Compound Formulation of Unani Medicine with special reference to epidemic/pandemic diseases, Journal of Drug Delivery and Therapeutics. 2020; 10(4):234-237 http://dx.doi.org/10.22270/jddt.v10i4.4223 *Address for Correspondence: Mohd Afsahul Kalam, Research Officer Unani & Lecturer Department of Ilmul Advia, Regional Research Institute of Unani Medicine (RRIUM), Habak, Naseembagh, Campus, Hazratbal, Srinagar, 190006, India INTRODUCTION Unani System of medicine is one of the oldest systems which is based on the Hippocratic theory of Akhlat-i-Arb‘a and Arkan-i-Arb‘a. This system of medicine included a great deal of ancient Egyptian medicine as well as important components of the ancient Mesopotamian traditions. The methods of treatment according to Unani System of Medicine is divided into four different parts namely Ilaj Bi‘l Ghiza (dietotherapy), Ilaj Bi‘t Tadbeer (regimenal therapy), Ilaj Bi‘l Yad (surgery) and Ilaj Bi‘l Dawa (pharmacotherapy). Considering pharmacotherapy, both single and compound drugs are being used. Among the poly-herbal drugs, various formulations such as Ma’jun, La‘uq, Taryaq, Khamira, Huboob, Aqras, Shayyaf, Sharbat, Araqiyat etc. are being used from centuries with great reputation for treatment of various systemic and local ailments. Among them Taryaq are the drugs which are used for treatment of various disorders including Amrad-i-Waba‘i, and other systemic disorders. Various forms of Taryaq are used like Huboob, Powder, and Ma’jun 1,2 . This formulation Taryaq-i-Waba‘i is made in the form of Huboob 3,4 . Huboob (pills) are small, round and uniformly shaped medicinal preparations, which are somewhat difference from Aqras (tablets) and Banadiq. Aqras are flat and circular in shape and Banadiq are round but bigger form of Huboob and weigh from one to three gram, but the weight of Huboob vary from one tenth of a gram to one gram 1 . Taryaq-i-Waba‘i, also mentioned as Taryaq-i-Afa’i by Hakim Azam Khan and Habb-i-Ta ‘un by Hakim Kabiruddin 3,4,5 . By almost physicians it is accepted