Original Article Effect of Dual Mesh Wrap on The Stability of Colonic Anastomosis Doğan Albayrak 1 , Bayram Türkeş 1 , Nuray Can 2 , İbrahim Ethem Cakcak 1 , Eyüp Kahya 1 , Serhat Oğuz 1 , Zeki Hoşcoşkun 1 1 Department of General Surgery, Trakya University School of Medicine, Edirne, Turkey 2 Department of Medical Pathology, Trakya University School of Medicine, Edirne, Turkey ORCID iDs of the authors: D.A. 0000-0002-1950-2444; B.T. 0000-0002-3949-1148; N.C. 0000-0003-2554-6432; İ.E.C. 0000-0001-8885- 514X; E.K. 0000-0001-5465-8017; S.O. 0000-0003-1346-2194; Z.H. 0000-0002-4673-3483. BACKGROUND/AIMS Colon anastomotic leakage is the cause of significant morbidity and mortality in surgery. Therefore, we aimed to demonstrate experi- mentally the effect of the conventional method of wrapping them through colo-colonic anastomosis performed by dual patch on anas- tomotic healing and security. MATERIAL and METHODS The study was conducted at the Experimental Animal Research Unit of the Medical Faculty of Trakya University, Edirne, Turkey. A total of 20 Wistar Albino adult rats were used. The rats were divided into 2 groups: 10 rats in the control group and 10 rats in the dual patch group. All rats underwent partial segmental colon resection, and colo-colonic anastomosis was performed in a single layer with 5/0 polypropylene. For rats in the dual patch group, the anastomosis was wrapped up with a 1-cm-wide dual patch. In the control group, there was no operation on the anastomosis. At 7 days after the procedure, the degree of peritoneal adhesion model previously prepared according to Evans devices laparotomy was used to observe all the rats and colon burst pressure. Both histopathological examination and the examination of the perianastomotic area were performed. RESULTS In the rats that were treated with dual mesh, there was a statistically significant increase in anastomotic line burst pressure (P<.05), a statistically significant increase in collagen amount (P<.05), and a statistically significant decrease in abdominal adhesions (P<.05). CONCLUSION As a result, the colo-colonic anastomosis of winding dual patch, without causing intra-abdominal adhesions, improves security by in- creasing the anastomosis bursting pressure. Keywords: Colorectal surgery, mesh, anastomotic leakage INTRODUCTION One of the most serious complications after colorectal surgery is anastomotic leakage, which is associated with high mor- bidity and mortality. In 1826, Denans (1) designed a device that performed colonic anastomosis without suture. In 1892, Mur- phy developed another device composed of 2 metallic rings that could connect the ends of the intestine with a button. Since then, many techniques for colonic anastomoses have been developed that aim to prevent or reduce the complications associated with anastomoses. More than half of postoperative deaths are caused by sepsis associated with anastomotic leakage (2). The frequency of anastomotic leakage after colonic resection was reported to be between 0.5% and 30% (1, 2). Various techniques have been proposed for anastomosis, and treatment modalities have been suggested to prevent anastomotic leakage. One treatment modality is wrapping the intestinal anastomosis with various prosthetic materials, such as polypropylene mesh (2). However, polypropylene mesh can cause intra-abdominal adhesions (3). In this study, we evaluated the effect of wrapping colonic anastomosis in a dual mesh on anastomotic stability. The dual mesh was not expected to cause intra-abdominal adhesions. Corresponding Author: Doğan Albayrak E-mail: albayrakdogan@hotmail.com Received: 27.05.2019 Accepted: 04.08.2019 DOI: 10.5152/cjms.2021.1049 13 Cite this article as: Albayrak D, Türkeş B, Can N, Cakcak İE, Kahya E, Oğuz S, et al. Effect of Dual Mesh Wrap on The Stability of Colonic Anastomosis. Cyprus J Med Sci 2021; 6(1): 13-7. Content of this journal is licensed under a Creative Commons Attribution 4.0 International License