Page 1 of 7 Determine Significant Factors Related to Malaria among Pregnant Women in Nigeria by Logistic Regression Analysis İlker Etikan*, Rukayya Alkassim, Özgür Tosun, Yavuz Sanisoğlu S and Meliz Yuvalı Department of Biostatistics, Near East University, Cyprus Introduction A life hostile parasitic infectious disease conveyed by female anopheles mosquitoes is called malaria [1]. In human body, malaria is caused by a protozoan of the Plasmodium type of the four subspecies, which include P.falciparum, P.vivax, P.malariae and P.ovale. The subspecie that causes greatest sickness and death in African countries was P. falciparum. This parasitic disease is transmitted by the bites of female anopheles mosquitoes of the genus Anopheles which is the most efficient and responsible for disease transmission in Africa [2]. Initially the parasite starts by infecting the liver where it begins to build up. After some days, the developing parasites are discharged into the blood stream to infect the red blood cells, where they continue to increase, ultimately bursting the red blood cells and infecting others in advance. If they reach high numbers, they may cause severe disease or even death as well [3]. One of the major health problems that cause both maternal and neonatal mortality is malaria during pregnancy. Low birth weight is one of the major factors that cause child mortality, where malaria during pregnancy reduces the birth weight. In Africa, maternal and neonatal mortality were associated with up to 300,000 death estimate in each year as indicated by statistics [4]. Luxemburger [5] make an estimate among Koran population living in Thailand, malaria during antenatal period have an effect on child mortality during the first month of child’s life [6]. Examined the Status of Pregnant Women having in Lagos State, Nigeria [7]. Examined the Inferiority of Single-Dose Sulfadoxine-Pyrimethamine Intermittent *Corresponding author: İlker Etikan, Department of Biostatistics, Near East University, Faculty of Medicine, Nicosia-TRNC, Cyprus. Received Date: : January 28, 2019 Published Date: February 15, 2019 ISSN: 2641-6336 DOI: 10.33552/ABBA.2019.01.000517 Annals of Biostatistics & Biometric Applications Research Article Copyright © All rights are reserved by İlker Etikan This work is licensed under Creative Commons Attribution 4.0 License ABBA.MS.ID.000517. Abstract Objectives: Malaria during antenatal period was a major health problem that lead to both mother and child death. The aim of this study is to assess the predictors of malaria during pregnancy among six states of Nigeria based on anti-malarial pill prescribed to pregnant women by the health facility. Methods: The analysis involves chi-square test for independent association between the predictors and risk of malaria diagnosis among the qualitative variables, Mann Whitney u test for quantitative variables and binary logistic regression for the multivariate analysis. Results: The analysis shows that the risk of malaria during pregnancy was significantly associated with Age, IPTp-up take, ITN use, source of energy for lightening, main material use for room’s rooftop and livestock keeping. This shows that, appropriate use of insecticide treated bed nets, optimal IPTp uptake against malaria and other protective measures, teamed with some elements such as sources of energy for lightening and main material for room’s rooftop decreased the incidence of malaria infectious disease among antenatal women. Conclusion: The research suggested that the illiterates and poor women are less probable of using these preventive measures in other to reduce the spread of malaria disease among pregnant women and entire population as whole. Keywords: Malaria; Pregnancy; Chi square test; Mann whitney - U test; Logistic regression