age was 63.5 (37-84). All pts were treated by open surgical approach: transabdomi- nal in 56 pt, retroperitoneal-lumbotomy-93 pts. Absolute indication has been seen in 26 pts (17.3%), relative in 34 pts (22.6%) and elective in 90 pts (60.1%). Results: Through the years 2001-2010 NSS were donein 6,7,2,15,9,9,13,23,32,34 pts/per year. Size of tumor was 4.5 (2.5- 4.5)cm in all pts. In 4 pts malignant altera- tion of renal cysts (size 4-7cm) has been confirmed by PH examination. Bilateral synchronous tumors were diagnosed in 3 pts and asynchronous in 5 pts. Hemostasis was done by suture, argon beam, “surgi- cel” tampon, and U shape suture. Average time of surgery was 2.8 hours (2-4 h). A minimal tumor free surgical margins was 1-3mm. Average blood transfusion was 250 ml (200-700 ml), time of warm isch- emia from 12-27 min, except for tumors smaller than 2.5cm where only manual compression was enough during hemosta- sis. All our pts are alive, with local recur- rence in 1pt (0.6%) and no distant metas- tases. Three pts (2%) developed severe bleeding and nephrectomyhas been done. Urine leakage ( 2 weeks) was seen in 3 pts (2%). Conclusion: NSS is a safe procedure in the hands of experienced urologists, with a small percent of complications, with excellent overall survival and should be used as standard procedure for localized RCC in selective indications. UP-01.192 Nephroureterectomy for Upper Tract TCC: Can We Predict Outcome? Drinnan N, Ghani K, Chopra N, Sarkar S, Le Roux P, Anderson C St. George’s University Hospital, London, UK Introduction and Objective: We deter- mine what surgical and pathological fac- tors might help predict outcome follow- ing nephroureterectomy (NU). Materials and Methods: We reviewed 94 patients, dividing into groups with or without previous bladder malignancy. Pri- mary tumour site, surgical technique, pathological grade and oncological out- come over an 11 year period, were ana- lyzed. Results: Primary tumour site was pelvica- lyceal (49), ureter (35) or both (10). Surgi- cal technique was Laparoscopic (49), Open (39) or Robotic (6).Distal ureteric excision was managed by open approach with bladder cuff (80), ureteric pluck (4), and in 10 ureteric stump was left behind. Of the 25 with previous bladder TCC (Group A) 10 (40%) had bladder recur- rences and 8 (32%) died from disease pro- gression. Of those without previous blad- der TCC (Group B) (69), new tumours in the bladder or cuff area occurred in 10 (14%). These were found in 11.9% of the cuff group, 66% of the pluck group and 14.2% of the stump group. Of Group B who developed new tumour (10), primary site was renal in 5, ureteric in 4 and com- bination in 1.3 of these patients died from disease progression, 1 had Grade-2 pathol- ogy and 2 had Grade-3. Of Group B pa- tients who had no evidence of recurrence (59), 10 died; 2 had inoperable disease, 6 had metastases, 2 from unrelated causes. Conclusion: The site of primary tumour has no bearing on local recurrence or metastases. Higher grade tumours carry worse prognosis.Excision of the distal ure- ter with bladder cuff confers lower risk of local recurrence. UP-01.193 Oncological Outcomes of Partial Nephrectomy for Tumors Greater than 4cm: A 10-Year Systematic Review El-Ghazaly T, Rendon R Dept. of Urology, Dalhousie University, Halifax, Canada Introduction and Objective: Partial ne- phrectomy (PN) is the standard of care for tumors smaller than 4-cm. Moreover, many medical associations (EAU, AUA, NCCN) have recommended nephron-spar- ing surgery for some tumors larger than 4cm amendable to PN. These recommen- dations are based on reports from several relatively small case series. We herein present a systematic review of literature for oncological outcomes of partial ne- phrectomy procedures performed for tu- mors larger than 4-cm, published over the past decade. Materials and Methods: A medline search was carried out using keywords “partial nephrectomy” and “nephron spar- ing” for records dating back to 1999. The search was limited to non-case report pa- pers, published in English. Inclusion crite- ria included PN performed for tumors larger than 4-cm, with oncological out- comes described. After removing dupli- cate results, 1463 titles and abstracts were further analyzed while filtering out techni- cal and perioperative studies. There were 108 papers finally scrutinized, and a total of 25 manuscripts were found to fulfill the inclusion criteria. These references were subsequently analyzed for patient population, statistical methods, tumor size, 5-year recurrence rates as well as overall and cancer-specific survival rates (OS, CSS). Sample contamination with smaller and/or benign masses was taken into consideration. Results: A total of 3118 patients with renal tumors larger than 4cm had under- gone PN between the years 1999, and 2010. This sample included 1756 with tumors between 4-7cm, 1169 patients with tumors larger than 7cm, and 193 patients with tumors greater than 4-cm (exact size unknown). Analysis revealed 5-yr OS rates of 91%, 92% and 91.4% for tumors 4-7cm, 7cm, and all tumors 4 respectively. The respective 5-yr CSS rates were 94%, 92%, and 93%. Conclusion: This systematic review re- veals excellent 5-yr overall and cancer- specific survival for patients with tumors 4 to 7-cm treated with PN. These out- comes compare favorably to those re- ported in historical radical nephrectomy (RN) series for similarly-sized tumors. for carefully selected tumors larger than 7-cm, similar outcomes have been reported. These excellent oncological outcomes, coupled with the advantages of renal function preservation support the use of PN for tumors from 4 to 7-cm, and even larger. UP-01.194 Laproendoscopic Single Site (LESS) Radical Nephrectomy and Radical Nephroureterectomy Ganpule A, Mishra S, Sabnis R, Desai M Muljibhai Patel Urological Hospital, Nadiad, India Introduction and Objective: Literature is abundant regarding application of LESS in variety of urological procedures. We assess the outcome of LESS radical ne- phrectomy done at our centre. Materials and Methods: A retrospective review of all these procedures done at our centre was done. Five LESS radical nephrectomies and one radical nephroureterectomy were done from Jan- uary 2009 till date. They were analyzed for the following parameters, size of tu- mour, hospital stay, operating room time, local and distant recurrence. The patients were followed up with a contrast-en- hanced CT scan at 1 year. Results: Radical nephrectomy was done in 5 patients, the mean age was 49.217.8yrs, mean body mass index (BMI) was 22.52.26kg/m 2 , mean tumour size was 5.581.84cm. The operating room time was15955.7min. In one pa- tient extra 5mm port was placed. The UNMODERATED POSTER SESSIONS S252 UROLOGY 78 (Supplement 3A), September 2011