Case Report
Subcutaneous Emphysema Induced by Cryotherapy:
A Complication due to Previous Punctures
Jared Martínez-Coronado, Bertha Torres-Álvarez, and Juan Pablo Castanedo-Cázares
Department of Dermatology, Hospital Central “Dr. Ignacio Morones Prieto”, Universidad Autonoma de San Luis Potos´ ı,
2395 Venustiano Carranza Avenue, 78210 San Luis Potos´ ı, SLP, Mexico
Correspondence should be addressed to Juan Pablo Castanedo-C´ azares; castanju@yahoo.com
Received 17 March 2015; Accepted 1 June 2015
Academic Editor: Mario Vaccaro
Copyright © 2015 Jared Mart´ ınez-Coronado et al. Tis is an open access article distributed under the Creative Commons
Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is
properly cited.
Cryosurgery is a common therapeutic modality used in dermatology; therefore we must be aware of its possible adverse efects. We
report a case of a patient with subcutaneous emphysema which occurred following the application of cryotherapy afer multiple
punctures of local anesthetic and intralesional steroids in a chest keloid scar. Despite the fact that this condition was gradually
resolved afer expectant observation, we warn about this complication when sprayed cryotherapy is preceded by multiple punctures
on cutaneous lesions above bony surfaces. In similar settings, cryotherapy must be frst administered or a cotton-tip applicator
should be used.
1. Introduction
Modern cutaneous cryosurgery was introduced in the 1960s
[1], since then it is commonly used by most dermatologists
around the world. It is recognized that this treatment was frst
applied in 1974 for keloidal scars by Pirece [2]. Cryotherapy
induces vascular damage that leads to anoxia and tissue
necrosis reducing the keloidal scar thickness [2, 3]. Tus, it
is not an innocuous treatment and dermatologist must be
aware of its side efects which can be immediate or delayed.
Frequent short-term adverse features include pain, syncope,
hemorrhage, edema, blistering, fever, infection, and pyogenic
granuloma [1, 3]; long-term changes consist in permanent
hypo- or hyperpigmentation, pseudoepitheliomatous hyper-
plasia, milia, nerve damage, alopecia, scar formation, and car-
tilage necrosis [1, 3]. We report a patient with keloid scar who
presented subcutaneous emphysema afer cryotherapy appli-
cation, an uncommon complication fnding in dermatologic
literature [4–7].
2. Case Report
A 28-year-old woman presented with an 18-month history
of 2 × 10 cm keloid scaring induced by acne vulgaris
on the upper frontal thorax. Her lesion was frst locally
anesthetized with intralesional lidocaine and aferwards
infltrated with acetonide of triamcinolone, followed by
two 40-second cycles of sprayed cryotherapy. Te patient
came back to our facilities 30 minutes afer the procedure
because the upper area of the treated zone started to bulk.
Physical examination only revealed swelling and cutaneous
crepitus on palpation. Tere was no erythema or pain, nor
local increased temperature. Vital signs were normal and
there were no systemic symptoms other than minor anxiety
triggered by this outcome. We made clinical diagnosis of
subcutaneous emphysema as a complication of cryotherapy
due to the timeline of the clinical history: punctures followed
by sprayed cryotherapy and then a prompt presence of local
subcutaneous emphysema. Te patient was retained in our
facilities and afer one hour of observation the skin became
normal in appearance. However, subcutaneous crepitation
continued upon complete resolution afer three days. Clinical
changes are shown in Figure 1.
3. Discussion
Subcutaneous emphysema (SE) is defned by the presence
of air or other gases within the sof tissue compartment
Hindawi Publishing Corporation
Case Reports in Dermatological Medicine
Volume 2015, Article ID 374817, 3 pages
http://dx.doi.org/10.1155/2015/374817