European Journal of Molecular & Clinical Medicine ISSN 2515-8260 Volume 07, Issue 06, 2020 1118 Qualitative analysis of the psychological stress and impact of psychiatric and psychological interventions on treatment of oral potentially malignant disorders. Dr. Sanat Kumar Bhuyan 1, Dr. Surjeet Sahoo2* Dr. Ruchi Bhuyan 3 ,Dr. Soumaya Ranjan Dash4, Snehalata Choudhury5. Sidhant Bhuyan 6 1 , Department of Oral Medicine & Radiology, Institute of Dental Sciences, Siksha “O”Anusandhan University (Deemed to be), K8, Kalinganagar, Bhubaneswar-751003, Odisha, 2 *. CORRESPONDING AUTHOR -Prof. & HOD Psychiatry, IMS & SUM Hospital. Siksha “O” Anusandhan University (Deemed to be), K8, Kalinganagar, Bhubaneswar-751003, Odisha, 3 . Department of Oral Pathology & microbiology, Institute of Medical Sciences, Siksha “O” Anusandhan University (Deemed to be), K8, Kalinganagar, Bhubaneswar-751003, Odisha, India Phno. 9437213002 *ruchibhuyan @soa.ac.in 4 . Senior resident, Department of Psychiatry, IMS & SUM Hospital. 5 . Clinical Psychologist, Department of Psychiatry, IMS & SUM Hospital. 6 . Medical student ,Neplganj Medical College Nepalganj, Nepal Abstract: Human mental stress is a major factor in recent busy life. Stress analysis and management in many ways are under study. However, except for OLP, studies suggesting the relationship between stress and the other oral PMD are very few. Studies directed towards the psychological management of this stress factor and there influence on current treatment strategies are also lacking. In this study, we will try to establish relationship of oral PMD to stress. Secondly, this will also try to look into the aetiology of the disorder in psychological dimension. Thirdly, we want to see the impact of psychiatric and psychological interventions on treatment of the condition. This study will have a substantial impact not only in understanding the aetiology of the disorder but also on the current standard treatment methods. The aim of this paper is to assess the level of anxiety and depression in patients with oral PMD and then compare the treatment outcome in these patients receiving the standard dental treatment with appropriate psychiatric treatment. To assess the impact of these treatments we also compare the treatments of both the groups to a control group. Keywords: psychological stress ,psychological interventions, oral potentially malignant disorders. 1. INTRODUCTION: Oral potentially malignant disorders include leukoplakia, erythroplakia, palatal lesions in the reverse smoker, submocous fibrosis, acinic keratose, lichen planus, discoidal lupus erythematosus, immunodeficiency in the context of cancer pre-disorder. oral disease is an