SUMMARY Background. The NeuroTrax TM Mindstreams TM computerized cognitive assess- ment system was designed for widespread clinical and research use. A require- ment for its use in longitudinal testing is demonstration of good test-retest reliability. To minimize practice effects, alternate forms of Mindstreams tests were administered on serial testing sessions. The present study evaluated the equivalence of the alternate forms in the context of test-retest reliability. Methods. A 2-center study was designed to evaluate test-retest reliability. 57 healthy participants (mean age 55.12 years) were tested twice with a wide range of Mindstreams tests. Analysis consisted of Pearson correlations. Results. Mindstreams outcome measures showed high test-retest corre- lations. Index scores that summarized performance in each cognitive domain showed good reliability: Memory r = 0.84, Executive Function r = 0.80, Visu- al Spatial r = 0.64, Verbal r = 0.40, Attention r = 0.79, Information Processing Speed r = 0.68, Motor Skills r = 0.80. Conclusion. Mindstreams computerized assessment is reliable for longi- tudinal testing. BACKGROUND The need for rapid screening of cognitive deficits is widespread, spanning the range of clinical services from mental health clinics to medical offices of individual practitioners and hospitals. Cognitive impairments accompany a wide variety of medical conditions, but since their assessments require time RELIABILITY OF A NOVEL COMPUTERIZED NEUROPSYCHOLOGICAL BATTERY FOR MILD COGNITIVE IMPAIRMENT A. Schweiger 1 , G.M. Doniger 2 , T. Dwolatzky 3 , D. Jaffe 4 , E.S. Simon 2 1 Department of Behavioral Sciences, Academic College of Tel Aviv, Tel Aviv, Israel 2 Department of Clinical Science, NeuroTrax Corporation, New York, NY USA 3 Memory Disorders Clinic and Department of Geriatrics, Shaare Zedek Medical Center, Jerusalem, Israel 4 School of Public Health, Hebrew University - Hadassah Medical School, Jerusalem, Israel Key words: cognitive deficits, test-retest reliability, longitudinal testing 407 ORIGINAL ARTICLE ACT ACTA Volume 1, Number 4, 2003, 407-413 NEUROPSYCHOLOGICA NEUROPSYCHOLOGICA